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2000
Volume 3, Issue 3
  • ISSN: 2666-8629
  • E-ISSN: 2666-8637

Abstract

Introduction

(English Marigold), or “Pot Marigold,” is a well-known herbal plant from the family of Asteraceae, which has been used for thousands of years as a medicinal herb. It is one of the most widely used aromatic herbs in the Ayurvedic system of medicine, which is based on the ethnological significance of the plant. Extracts of this plant have been found to possess a range of therapeutic benefits, including anti-hyperlipidaemia, cardiovascular and antidiabetic properties, as well as antioxidant and anti-inflammatory properties. Additionally, it has been found to be effective in wound healing and has anti-cancer, anti-hepatitis, antibacterial, and antiretroviral properties. Traditionally, it has been used as a herbal remedy to treat skin tumours and dermatological lesions as well as ulcers and swellings, as well as nervous disorders.

Aims

In addition to ethnopharmacology, pharmacology, and toxicology, this abstract also covers the morphology, microscopy, phytoconstituents, pharmacological reports, phytochemistry, and toxicity of the well-known species. Cosmetic ingredients derived from the C officinalis plant include extracts, flower oil, seed oil, and other components of the plant. These components include minerals, carbohydrates, and lipids; phenolic acids; flavonoids; tannins; coumarins; sterols; steroids; monoterpenes; sesquiterpene; triterpenes; tocopherol; quinones; amino acids; and resins. A chemical analysis of these ingredients reveals a wide variety of chemical compounds, including amino acid, triterpenoid, quinone, flavonoid, volatile oil, carotenoid, and other chemicals. Some species have medicinal value, and a literature review highlights their utilization.

Results

has a wide range of medicinal properties, ranging from antibacterial and antifungal properties to anthelmintic and antiviral properties. Additionally, it has antioxidant and hepatoprotective properties, as well as cardioprotective and wound-healing properties. Furthermore, it has been used to treat gastrointestinal, eye, and skin diseases. The plant has the potential to be a significant medicinal resource for mankind. It exhibits anti-HIV, cytotoxic, anti-inflammatory, hepatoprotective, and spasmolytic properties. The plant is used in almost 200 cosmetic formulations and has the potential for further research.

Conclusion

This review emphasizes the future scope of species, focusing on their multifarious biological activities and potential applications as medicinal agents. This research fills gaps in existing studies, allowing researchers to validate traditional claims and advance the safe and effective use of CO in treating various ailments.

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References

  1. AgrawalO.P. RajuP.S. Global market of herbal products: Opportunities for Indian Traditional System of Medicine.New Delhi, IndiaNarcosa Publishing House2006510
     [Google Scholar]
  2. BasuB.D. Indian Medicinal Plants. Dehradun, India:International Book Distributor1993Vol. II14131414
     [Google Scholar]
  3. The Wealth of IndiaRaw Materials, A Dictionary of Indian Raw Material & Industrial Products. New Delhi.Publications & Information Directorate CSIR199235558
     [Google Scholar]
  4. AshwlayanV.D. KumarA. VermaM. GargV.K. GuptaS.K. Therapeutic potential of Calendula officinalis.Pharm. Pharmacol. Int. J.201862149155.org/10.15406/ppij.2018.06.00171
     [Google Scholar]
  5. WikipediaCalendula officinalis.2009Available From: http://en.wikipedia.org/wiki/Calendula_officinalis
    [Google Scholar]
  6. Editorial BoardsPDR for Herbal Medicines.2nd edMontvaleThomson-Medical Economics2003497500
     [Google Scholar]
  7. ManiA. PawarB. Marawar SharmaA. RaniA. AroraD. A review on phytochemistry and ethnopharmacological aspects of genus Calendula.Pharmacogn. Rev.201371417918710.4103/0973‑7847.120520
     [Google Scholar]
  8. KhairnarM.S. Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent.J. Indian Soc. Periodontol.201317674174710.4103/0972‑124X.124491
     [Google Scholar]
  9. BasuB.D. Indian Medicinal Plants. Dehradun, India.International Book Distributor1993Vol. II14131414
     [Google Scholar]
  10. Al-SnafiA.E. Calendula officinalis’s chemical components and pharmacological effects: A review.Indian J Pharmaceut Sci Res201553172185
     [Google Scholar]
  11. AroraD. RaniA. SharmaA. an overview of the ethnopharmacology and phytochemistry of the genus Calendula.Pharmacogn. Rev.201371417910.4103/0973‑7847.120520 24347926
     [Google Scholar]
  12. SamochowiecL. Pharmacological study of saponifies from Aralia manshurica rupr.et maxim. and Calendula officinalis.L Herbal Pol198329151155
     [Google Scholar]
  13. IaukL. Lo BueA.M. MilazzoI. RapisardaA. BlandinoG. Antibacterial activity of medicinal plant extracts against periodontopathic bacteria.Phytother. Res.200317659960410.1002/ptr.1188 12820224
     [Google Scholar]
  14. GazimZ.C. RezendeC.M. FragaS.R. SvidzinskiT.I.E. CortezD.A.G. Antifungal activity of the essential oil from Calendula officinalis L. (asteraceae) growing in Brazil.Braz. J. Microbiol.2008391616310.1590/S1517‑83822008000100015 24031180
     [Google Scholar]
  15. PreethiK.C. KuttanG. KuttanR. Antioxidant potential of an extract of Calendula officinalis. flowers in vitro. and in vivo.Pharmaceut Biol.2006449691697
     [Google Scholar]
  16. HusseinM.S. El-TawilO.S. El-Hoda YassinN. AbdouK.A. The study investigates the protective effect of Morus alba and Calendula officinalis plant extracts on carbon tetrachloride-induced hepatotoxicity in isolated rat hepatocytes.J. American Sci.2010610762763
     [Google Scholar]
  17. ChakrabortyG.S. AroraR. MajeeC. Anti-diabetic and Anti-hyperlipidaemic Effect of Hydroalcoholic extract of Calendula officinalis.Int ResJ Pharm2011216165
     [Google Scholar]
  18. Al-SnafiA.E. The chemical constituents and pharmacological effects of Calendula officinalis -a review.Indian J Pharmaceut Sci Res201553172185
     [Google Scholar]
  19. PurwalL. ShrivastavV. MakondeK.K. JainU. Anthelmintic activity of aqueous extracts of some Saponin containing medicinal plants.Pharm. Lett.201024476481
     [Google Scholar]
  20. KalvatchevZ. WalderR. GarzaroD. Anti-HIV activity of extracts from Calendula officinalis flowers.Biomed. Pharmacother.199751417618010.1016/S0753‑3322(97)85587‑4 9207986
     [Google Scholar]
  21. BeudotC. De MéoM.P. DauzonneD. Evaluation of the mutagenicity and antimutagenicity of forty-two 3-substituted flavones in the Ames test.Mutat. Res. Genet. Toxicol. Environ. Mutagen.19984172-314115310.1016/S1383‑5718(98)00103‑X 9733954
     [Google Scholar]
  22. ChandranP.K. KuttanR. Effect of Calendula officinalis flower extract on acute phase proteins, antioxidant defence mechanism and granuloma formation during thermal burns.J. Clin. Biochem. Nutr.2008432586410.3164/jcbn.2008043 18818737
     [Google Scholar]
  23. AlexenizerM. DornA. Screening of medicinal and ornamental plants for insecticidal and growth regulating activity.J. Pest Sci.200780420521510.1007/s10340‑007‑0173‑x
     [Google Scholar]
  24. Pérez-GutiérrezS. Vargas-SolísR. ZavalaS.M. Pérez-GC. Pérez-GR.M. Inhibitory effect of five plant extracts on heart rates of rats.Phytother. Res.199812S1S49S5010.1002/(SICI)1099‑1573(1998)12:1+<S49::AID‑PTR248>3.0.CO;2‑B
     [Google Scholar]
  25. BogdanovaN.S. NikolaevaI.S. ShcherbakovaL.I. TolstovaT.I. MoskalenkoN.Iu. PershinG.N. [Study of antiviral properties of Calendula officinalis].Farmakol. Toksikol.1970333349355 4318166
     [Google Scholar]
  26. KhareC.P. Encyclopaedia of Indian Medicinal Plants.GermanySpringer-Verlag Publisher2004116117
     [Google Scholar]
  27. ĆetkovićGS DjilasSM Čanadanović-BrunetJM TumbasVT Antioxidant properties of marigold extracts.Food Res Int20043776435010.1016/j.foodres.2004.01.010
     [Google Scholar]
  28. JohnR. JanN. JohnR. Calendula officinalis-an important medicinal plant with potential biological properties.Proc. Indian Natl. Sci. Acad. A Phys. Sci.201793076978710.16943/ptinsa/2017/49126
     [Google Scholar]
  29. AdelaP. BeleC. SandaA. CarmenS. Carotenoids in four Calendula officinalis L. flower types were analysed using HPLC.Acta Biol. Szeged.200347471437
     [Google Scholar]
  30. BabaeeN. MoslemiD. Anti-oxidant In patients with head and neck malignancies, the ability of Calendula officinalis flowers extract and prevention of radiation-induced oropharyngeal mucositis: A randomised controlled clinical study.Daru2013211182410.1186/2008‑2231‑21‑18 23497687
     [Google Scholar]
  31. LimaM. DosR. LopesA.P. MartinsC. BritoG.A.C. CarneiroV.C. The Effect of Calendula officinalis on Oxidative Stress and Bone Loss in Experimental Periodontitis.Front. Physiol.201780044010.3389/fphys.2017.00440
     [Google Scholar]
  32. SainiP. Al-ShibaniN. SunJ. Effects of Calendula officinalis on human gingival fibroblasts.Homeopathy20121012929810.1016/j.homp.2012.02.003 22487368
     [Google Scholar]
  33. PanahiY. SharifM.R. SharifA. A randomized comparative trial on the therapeutic efficacy of topical aloe vera and Calendula officinalis on diaper dermatitis in children.ScientificWorldJournal201220121510.1100/2012/810234 22606064
     [Google Scholar]
  34. PommierP. GomezF. SunyachM.P. D’HombresA. CarrieC. MontbarbonX. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.J. Clin. Oncol.20042281447145310.1200/JCO.2004.07.063 15084618
     [Google Scholar]
  35. SinghM. BagewadiA. Comparison of effectiveness of Calendula officinalis extract gel with lycopene gel for treatment of tobacco-induced homogeneous leukoplakia: A randomized clinical trial.Int. J. Pharm. Investig.201772889310.4103/jphi.JPHI_19_17 28929051
     [Google Scholar]
  36. BabaeeN. MoslemiD. KhalilpourM. Antioxidant capacity of Calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: A randomized controlled clinical study.Daru20132111810.1186/2008‑2231‑21‑18 23497687
     [Google Scholar]
  37. GiostriG.S. NovakE.M. BuzziM. Guarita-SouzaL.C. Treatment of acute wounds in hand with Calendula officinalis L.: A randomized trial.Tissue Barriers2022103199482210.1080/21688370.2021.1994822 34674610
     [Google Scholar]
  38. BuzziM. de FreitasF. de Barros WinterM. Therapeutic effectiveness of a Calendula officinalis extract in venous leg ulcer healing.J. Wound Care2016251273273910.12968/jowc.2016.25.12.732 27974009
     [Google Scholar]
  39. De AngelisC. Di StadioA. VitaleS. Use of Calendula ointment after episiotomy: A randomized clinical trial.J. Matern. Fetal Neonatal Med.202235101860186410.1080/14767058.2020.1770219 32460565
     [Google Scholar]
  40. SaffariE. Mohammad-Alizadeh-CharandabiS. AdibpourM. MirghafourvandM. JavadzadehY. Comparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial.Women Health201757101145116010.1080/03630242.2016.1263272 27880086
     [Google Scholar]
  41. AbediP. PazhohidehZ. MohammadiS. BahramiN. MojabF. MaraghiE. The effect of Calendula officinalis versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial.J. Adv. Pharm. Technol. Res.201891151910.4103/japtr.JAPTR_305_17 29441319
     [Google Scholar]
  42. ChandranP.K. KuttanR. Effect of Calendula officinalis flower extract on acute phase proteins, anti-oxidant defense mechanism and granuloma formation during thermal burns.J. Clin. Biochem. Nutr.2008432586410.3164/jcbn.2008043 18818737
     [Google Scholar]
  43. DindaM. MazumdarS. DasS. The water fraction of Calendula officinalis hydroethanol extract stimulates in vitro and in vivo proliferation of dermal fibroblasts in wound healing.Phytother. Res.201630101696170710.1002/ptr.5678 27426257
     [Google Scholar]
  44. FonsecaY.M. CatiniC.D. VicentiniF.T.M.C. NomizoA. GerlachR.F. FonsecaM.J.V. Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: Evaluation of reduced glutathione levels and matrix metalloproteinase secretion.J. Ethnopharmacol.2010127359660110.1016/j.jep.2009.12.019 20026397
     [Google Scholar]
  45. ParenteL.M.L. AndradeM.A. BritoL.A.B. Angiogenic activity of Calendula officinalis flowers L. in rats.Acta Cir. Bras.2011261192410.1590/S0102‑86502011000100005 21271199
     [Google Scholar]
  46. ParenteL.M. Lino Junior RdeS. TresvenzolL.M. VinaudM.C. de PaulaJ.R. PauloN.M. Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil.Evid. Based Complement. Alternat. Med.20122016375671
     [Google Scholar]
  47. PreethiK.C. KuttanR. Wound healing activity of flower extract of Calendula offlcinalis.J. Basic Clin. Physiol. Pharmacol.2009201738010.1515/JBCPP.2009.20.1.73 19601397
     [Google Scholar]
  48. ShafeieN. Tabatabai NainiA. JahromiH. Comparison of different concentrations of Calendula officinalis gel on cutaneous wound healing.Biomed. Pharmacol. J.20158297999210.13005/bpj/850
     [Google Scholar]
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Boon Plant Calendula officinalis Linn. (CO): An Investigation, Ethnopharmacological, Phytoconstituent Review’
Curr Func Foods 3, E26668629298407 (2025); https://doi.org/10.2174/0126668629298407240902102850
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  • Article Type:     Review Article
Keyword(s): Asteraceae; Calendula officinalis; Pharmacological activities; Phytochemical constituents; Pot Marigold; Traditional Medicine

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