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2000
Volume 28, Issue 9
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Medicinal plants play a crucial role in traditional medicine, where they are extensively employed by traditional physicians for treating a wide array of ailments. (Linn), commonly known as the Wood apple and belonging to the Rutaceae family, is widely cultivated in countries, such as Pakistan, India, and Sri Lanka. The various parts of including its roots, leaves, fruits, stem, and even the whole plant, have been traditionally used in the treatment of numerous conditions, such as constipation, diarrhea, dysentery, skin diseases, asthma, astringent, diabetes, jaundice, and dyspepsia and act as diuretic agents, cardiotonic, cardiac stimulant, and hepato-protectant. Extensive research has revealed that possesses a rich chemical composition, including quinones, lignans, flavonoids, sterols, coumarins, alkaloids, triterpenoids, phenolic acids, and volatile oils, present in its stem, leaves, fruits, stem bark, and roots. These chemical constituents contribute to its diverse therapeutic properties. In recent years, numerous studies have explored the ethano-pharmacological properties of extracts, highlighting their anticancer, antidiabetic, anti-diarrheal, antimicrobial, antiulcer, wound healing, antioxidant, hepatoprotective, antibacterial, antifungal, larvicidal, neuroprotective, antispermatogenic, antihistaminic, diuretic, and adsorbent activities. This comprehensive review focuses on the traditional uses, biological activities, and phytoconstituents isolated from different parts of Linn. The gathered information provides valuable insights into the therapeutic potential of this plant, serving as a foundation for further research and the development of novel pharmaceuticals. The integration of traditional knowledge with scientific evidence enhances the understanding of the medicinal properties of fostering its utilization in modern medicine and healthcare systems.

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/content/journals/cchts/10.2174/0113862073285538240417051928
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Ethnobotanical Significance, Phytopharmacology, and Toxicological Profile of Limonia acidissima L. (Rutaceae): A Review
Comb Chem High Throughput Screen 28, 1459 (2025); https://doi.org/10.2174/0113862073285538240417051928
/content/journals/cchts/10.2174/0113862073285538240417051928
/content/journals/cchts/10.2174/0113862073285538240417051928
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  • Article Type:     Review Article
Keyword(s): chemical constituent; Herbal medicine; Limonia acidissima; nutritional information; pharmacological activity; toxicity profile

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