Skip to content
2000
Volume 28, Issue 7
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Background

Quality control is a system of validated procedures in which many samples, including active pharmaceutical ingredients and final products, are analyzed using standard or validated analytical methods.

Methods

Analytical methods used in analyzing active pharmaceutical ingredients or final products in the pharmaceutical industry can be methods registered in pharmacopeias and developed by the company itself. For this reason, published papers related to pharmaceutical analysis attract analysts and researchers' attention. In this study, pharmaceutical analysis and bioanalysis studies carried out between 2015 and 2023 were examined using Google Scholar, and the recent trends were determined for pharmaceutical analysis. Among the published papers performing conventional analytical techniques for pharmaceutical analysis, those applying UV-VIS spectrophotometry method were selected to predict a future perspective in this study. In addition to the data obtained, the current situation of the pharmaceutical industry was considered to correlate with the obtained data for pharmaceutical analysis.

Results

The results were presented with comparative tables and summarizing graphs. Interpreting the results allowed us to determine the trends that pharmaceutical analysis studies will lead in the future. This study can be helpful for researchers working on pharmaceutical analysis in both the industry and academia to predict future trends in pharmaceutical analysis. As a result of the literature research covering the dates 2015-2023, 56% of UV-VIS Spectrophotometric methods are used on pharmaceutical dosage forms, 27% are bulk, 16% are pure, 2% are biological materials, and 0.4% are herbal made from materials. Of these studies, 28% were conducted in the 200-240 nm range, 27% were conducted in the 240-300 nm range, and only 44% were conducted at >300 nm. Interpreting the results allowed us to determine the trends that pharmaceutical analysis studies will lead in the future.

Conclusion

This study can be helpful for researchers working on pharmaceutical analysis in both the industry and academy side to predict future trends for pharmaceutical analysis.

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/cchts/10.2174/0113862073285152240514171505
2025-05-01
2025-10-03

  • From This Site

    /content/journals/cchts/10.2174/0113862073285152240514171505
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. MehdiZ.S. Analytical method development for the spectrophotometric determination of sulfamethoxazole in bulk drug and pharmaceutical preparation.J. Chem. Biochemistry201531637410.15640/jcb.v3n1a5
     [Google Scholar]
  2. DamorD.K. MashruR.C. Method development and validation of simultaneous estimation of cilostazol and telmisartan.Int. Bull. Drug Res201551222
     [Google Scholar]
  3. AvasaralaH. JayanthiV.R. The development and validation of a spectrophotometric method for a novel anti psychotic drug asenapine maleate.Int. J. Chemtech Res.20158549553
     [Google Scholar]
  4. BagchiA. MukherjeeP. RahaA. Development and validation of uv spectrophotometric method for estimation of erythromycin in bulk drug and pharmaceutical formulation.Int. J. Rec. Adv. Pharm. Res.2015537176
     [Google Scholar]
  5. KumarR. SubramanianN. Role of UV-Visible Spectrophotometry in the determination of Lincomycin Hydrochloride in bulk and tablet dosage forms.Int. J. Pharm. Tech. Res.201587175179
     [Google Scholar]
  6. DeshpandeS. Development and validation for simultaneous estimation of telmisartan and hydro-chlorothiazide in bulk drug and pharmaceu-tical dosage form by UV-spectrophotometry.Intl. J. Pharmaceuti. Drug Ana.2015312362265
     [Google Scholar]
  7. JaniB. ShahK. KapuparaP. Development and validation of UV spectroscopic method for simultaneous estimation of dapagliflozin and metformin hydrochloride in synthetic mixture.Intl. J. Res. Develop. Pharma. Life Sci.20154315691576
     [Google Scholar]
  8. SriK.V. JainG.V. MadhuriM. UV-Visible Spectrophotometric Method for the Estimation of Rilpivirine Hydrochloride in Pharmaceutical Dosage Form by Using Multivariate Technique.Chem. Sci. Trans.201543799805
     [Google Scholar]
  9. PekamwarS. Validated UV-Visible spectrophotometric method for simultaneous estimation of cefixime and moxifloxacin in pharmaceutical dosage form.J. Appl. Pharmaceutical Science2015513741
     [Google Scholar]
  10. ShindeN.G. AloorkarN. Development and validation of UV spectrophotometric method for simultaneous estimation of propranolol hydrochloride and rosuvastatin calcium in bulk drug and pharmaceutical dosage form.International J. Appl. Pharmaceutics2015455559
     [Google Scholar]
  11. BhattD.A. Development and validation of spectrophotometry method for simultaneous estimation of cefepime hydrochloride and amikacin sulphate.World J. Pharm. Res.20154514821491
     [Google Scholar]
  12. HardeM. WankhedeS. ChaudhariP. Development of validated UV spectrophotometric method for simultaneous estimation of Ibuprofen, Paracetamol and Caffeine in the bulk drug and marketed formulation.World J. Pharm. Res.20154914281436
     [Google Scholar]
  13. ThamkeN. UV method for determinationin of methotrexate tablet dosage form.Med. Chem.201541110421047
     [Google Scholar]
  14. ChavhanB.R. Development and Validation of analytical method for Simultaneous Estimation of Glibenclamide and Metformin HCl in Bulk and Tablets using UV–visible spectroscopy.WJPR2015412571266
     [Google Scholar]
  15. MaharjanS. Formulation and in-vitro evaluation of self emulsifying drug delivery system of furosemide.World J. Pharm. Res.201550215681579
     [Google Scholar]
  16. RamadanA.A. MandilH. SabouniJ. Determination of atorvastatin calcium in pure and its pharmaceutical formulations using iodine in acetonitrile by UV-Visible spectrophotometric method.Int. J. Pharm. Pharm. Sci.201579427433
     [Google Scholar]
  17. NeelakandanS. SmithA.A. Development of analytical method for pyrantel embonate using UV-spectrophotometry.AJPST201553120123
     [Google Scholar]
  18. BaigM.S. Simultaneous estimation of azithromycin and cefpodoxime proxetil from its tablet dosage form by UV visible spectroscopic methods.World J. Pharm. Pharmaceut. Sci., WJPPS2015414201430
     [Google Scholar]
  19. JaniB. ShahK. KapuparaP. Development and validation of UV spectroscopic first derivative method for simultaneous estimation of dapagliflozin and metformin hydrochloride in synthetic mixture.J. Bioequiv.201511102
     [Google Scholar]
  20. NaulayYeswanthKumarM. PashaS.A. Development and validation of UV spectrophotometric method for the simultaneous estimation of hydrochlorothiazide and propranolol in bulk and formulation by simultaneous equation method.IJPCBS201553504509
     [Google Scholar]
  21. GadveS. Development of uv--visible spectrophotometric method for the analysis of methotrexate in tablet formulations.Intl. J. Pharmaceut., Chem. Biol. Sci.201554982985
     [Google Scholar]
  22. GangradeD.M. BakshiS.D. Dissolution method development followed by spectrophotometric analysis and validationofbetahistine hydrochloride controlled release tablets.IJCPA201523168173
     [Google Scholar]
  23. PakhaleB.A. ShinkarD. SaudagarR. Development and validation of spectrophotometric method for determination of venlafaxine hydrochloride.Int. J. Pharm. Sci. Res.201566669
     [Google Scholar]
  24. PatelM. Development and validation of two uv spectrophotometric methods for simultaneous estimation of ilaprazole, and levosulpiride in tablet dosage form.World J. Pharm. Res.202111114751487
     [Google Scholar]
  25. VermaG. MishraM. Development and optimization of UV-Vis spectroscopy-A review.World J. Pharm. Res.201871111701180
     [Google Scholar]
  26. AkashM.S.H. RehmanK. Essentials of pharmaceutical analysis.Springer202010.1007/978‑981‑15‑1547‑7
     [Google Scholar]
  27. BaigM.S. Simultaneous estimation of levofloxacin and cefpodoxime proxetil from its tablet dosage form by UV visible spectroscopic methods.World J. Pharm. Pharm. Sci.2015415621572
     [Google Scholar]
  28. SchadendorfD. FisherD.E. GarbeC. GershenwaldJ.E. GrobJ.J. HalpernA. HerlynM. MarchettiM.A. McArthurG. RibasA. RoeschA. HauschildA. Melanoma.Nat. Rev. Dis. Primers2015111500310.1038/nrdp.2015.327188223
     [Google Scholar]
  29. KarchaliyaC. PatelP. Development and Validation of Analytical Methods for Simultaneous Estimation of Amitriptyline Hydrochloride and Methylcobalamin in their Tablet Dosage Form by UV Spectrophotometric Method.PharmaTutor2015374650
     [Google Scholar]
  30. TariqM.H. Development and validation of a method for the analysis of vancomycin in human serum using ultracentrifuge protein precipitation and UV spectroscopy.Lat. Am. J. Pharm.201534814891496
     [Google Scholar]
  31. PandyaD. UV-Vis spectrophotometric assay determination of oral antiplatelet ticagrelor drug in pharmaceutical formulation: Application to content uniformity.J. Chemical Pharmaceutical Res.201681316321
     [Google Scholar]
  32. RaoK.M. Determination of clopidogrel by visible spectrophotometry in pure form and pharmaceutical formulations.J. Indian Chem. Soc.20169318
     [Google Scholar]
  33. ZamirG. Validated UV spectroscopic methods for determination of enzalutamide in pure and pharmaceutical dosage form.Anal. Chem.201616111
     [Google Scholar]
/content/journals/cchts/10.2174/0113862073285152240514171505
Loading
A Comprehensive Examination of UV-VIS Spectrophotometric Methods in Pharmaceutical Analysis Between 2015-2023
Comb Chem High Throughput Screen 28, 1125 (2025); https://doi.org/10.2174/0113862073285152240514171505
/content/journals/cchts/10.2174/0113862073285152240514171505
/content/journals/cchts/10.2174/0113862073285152240514171505
Loading

Data & Media loading...

Supplements

Supplementary material is available on the publisher's website along with the published article.

file format download Download

  • Article Type:     Review Article
Keyword(s): analytical method development; google scholar; Pharmaceutical analysis; statistics; UV-VIS spectrophotometry

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test