Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response

Shreya Kanodia; Laura M. Fahey; W. Martin Kast

doi:10.2174/156800907780006869

ISSN: 1568-0096
E-ISSN: 1873-5576

oa Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response
Authors: Shreya Kanodia¹, Laura M. Fahey² and W. Martin Kast³
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¹ Norris Comprehensive Cancer Center, ZNI 245, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA. ² Norris Comprehensive Cancer Center, ZNI 245, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA. ³ Norris Comprehensive Cancer Center, ZNI 245, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033, USA.
Source: Current Cancer Drug Targets, Volume 7, Issue 1, Feb 2007, p. 79 - 89
DOI: https://doi.org/10.2174/156800907780006869
- Available online: 01 Feb 2007

Abstract

The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for the decades required to develop HPV-related cancers, the virus must escape host immunity. HPV is a simple DNA virus that has evolved to escape immune attack by a combination of stealth and interference. This review focuses on the mechanisms by which HPV can evade recognition by the host immune system.

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2007-02-01

2025-09-02

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Article Type: Research Article

Keyword(s): cancer; immunotherapy; Papilloma virus; tumor immunology

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oa Mechanisms Used by Human Papillomaviruses to Escape the Host Immune Response

Abstract

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