Bioactive Compounds for Effective Management of Drug-Resistant Tuberculosis

Background: Tuberculosis is a granulomatous irresistible bacterial infection caused by Mycobacterium tuberculosis. The present anti-TB antibiotics are less useful in the treatment of Multi- Drug-Resistant (MDR) strains. Methods: We focused on distinguishing phyto-bioactive compounds dependent on customary uses and testing their concentrates against MDR strains. This will help abbreviate the present remedial regimens for TB and for treating HIV-TB co-disease. Results: This article is an endeavor to examine the antimycobacterial and immunomodulatory role of phyto-bioactive compounds as another option and feature them for additional examination for the management of drug-resistant tuberculosis. Conclusion: This review focused on the tubercle bacilli utilizing bioactive compounds as the therapeutic vehicle against MDR strains and also the synergistic action with available TB medications.