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2000
Volume 21, Issue 9
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

Background

belongs to the family Cucurbitaceae and is generally known as teasle gourd or spiny gourd. This plant is highly significant for its active phytoconstituents bearing several pharmacological activities.

Objectives

This study aims to evaluate the anthelmintic activity of biosynthesized Silver nanoparticles of fruit extract against .

Methods

silver nanoparticles were prepared by green synthesis and were characterized using spectroscopic methods like UV-visible, FTIR, and Scanning Electron Microscopy (SEM) techniques. The prepared silver nanoparticles were investigated for the targeted activity using Albendazole as standard and normal saline as the control.

Results

The UV-visible spectrophotometer showed absorbance in the range of 424 nm. FTIR revealed the presence of functional groups of both extract and nanoparticles. The spherical shape of the AgNPs and their size ranges below 100 nm by SEM. The anthelmintic activity showed the paralysis and mortality rate of the worms for the fruit extract, and silver nanoparticles were found to be 45.03 ± 0.1, 60.13 ± 0.1, and 12.35 ± 0.04, 22.34 ± 0.02 by One way ANOVA ( <0.0001).

Conclusion

The fruit extract converted to silver nanoparticles had better anthelmintic activity compared to the fruit extract. The paralysis and death time were reduced 4 to 5 times, which showed the improved effect of the silver nanoparticles of extract.

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Anthelmintic Effect of Biosynthesized Silver Nanoparticles of the Momordica dioica Fruit Extract
Curr. Bioact. Compd. 21, e15734072307303 (2025); https://doi.org/10.2174/0115734072307303241016053537
/content/journals/cbc/10.2174/0115734072307303241016053537
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  • Article Type:     Research Article
Keyword(s): AgNPs; anthelmintic activity; FTIR; in-vitro studies; Momordica dioica; SEM

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