Protocol for the Rat Episcleral Vein Cauterization Model of OHT/Glaucoma
- Authors: Anthonia Okolie1, Ya Fatou Njie Mbye2, Fatima Muili3, Catherine A. Opere4, Sunny E. Ohia5
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View Affiliations Hide Affiliations1 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, 3100 Cleburne Street, Houston, TX 77004, USA 2 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, 3100 Cleburne Street, Houston, TX 77004, USA 3 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, 3100 Cleburne Street, Houston, TX 77004, USA 4 Department of Pharmacy Sciences, School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska, USA 5 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Texas Southern University, 3100 Cleburne Street, Houston, TX 77004, USA
- Source: Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma - Ocular Hypertension , pp 311-314
- Publication Date: August 2025
- Language: English
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Glaucoma caused by ocular hypertension (OHT) poses a grave health problem as our society's demographics tilt towards an ever-increasing aged population. In order to study this ocular disease, several different models of OHT involving a variety of different animal species have been developed over the years. In the current chapter, we will focus on a method to raise intraocular pressure (IOP) by cauterizing two or three trunks of episcleral veins in the eye of rats to induce OHT.
Hardbound ISBN:
9789815324341
Ebook ISBN:
9789815324334
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