Highly Pathogenic Avian Influenza A (H5N8) Virus: Structure, Case Studies and WHO Recommendation

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The high transmissibility and pathogenicity of the H5N8 strain of the Avian Influenza virus pose serious threats to poultry populations worldwide. The introduction, traits, structure, history, features, prevalence, case studies, treatment, diagnosis, and WHO recommendations for H5N8 avian influenza are all covered in detail in this chapter. The virus mainly affects birds, resulting in severe symptoms like decreased egg production and respiratory discomfort. A multidisciplinary approach is required for diagnosis, which is essential for efficient management and surveillance. This approach includes clinical assessment, laboratory testing, and epidemiological investigation. Limited treatment options include antiviral drugs like zanamivir and oseltamivir, which are used off-label in birds. To track and contain zoonotic influenza outbreaks, the WHO recommends enhanced pandemic preparedness through risk assessment and intervention techniques, as well as international surveillance and cooperation.