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Surfactin Biosynthesis and its Potential Applications in Agriculture and Food System

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Surfactin is a biosurfactant of the lipopeptide-type that has excellent physicochemical properties and biological activity. However, surfactin’s high cost and low productivity of the wild strains restrict its large-scale manufacturing and application. Hence, numerous engineered bacteria have been utilized to boost surfactin biosynthesis. The current review includes information on the structure, physicochemical properties, and antibacterial mechanism of surfactin. This article also summarizes the regulatory network of surfactin biosynthesis, the molecular modification strategies, and the major function of surfactin, as well as its applications in agriculture, livestock, aquaculture and the food field. Finally, future prospects for surfactin research are discussed.

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