Bentham Science Publishers

This volume elaborates upon functioning of a quantum computer and the analysis of mind phenomenon in a natural scientific paradigm. Many outstanding physicists - Bohr, Heisenberg et al.- considered that many aspects of quantum physics could be understood considering the laws of perception, linguistics and semiotics within the world's semiotic description. An analysis of would-be scientific theories and paradoxes connected with a number of unformulated statements regarding initial information is therefore presented. These, in turn, could be used to draw algorithms that generate a picture of reality in the human mind.The eBook also attempts to find out what is available to an observer from his/her standpoint (reference system), and from what theoretical standpoints that observation is developed. The initial point of this approach is recognizing that we are closed inside the semiotic system in which the ‘universe’ can only be presented to our mind. Such semiotic restrictions for translation of knowledge in any field are considered.This book is intended as a resource for senior students and researchers in natural sciences, scientific philosophy and contemporary psychology.

Conceptual Design of Green Transport Airplanes presents key information, methodologies, and modern tools for the conceptual design of airliners that comply with requirements to minimal environmental impact. The book is comprised of eight chapters that address relevant subjects such as airplane technological evolution, feasibility studies, design framework for conceptual design, and flight operations. Important issues and methods for an in-depth feasibility study are presented to facilitate the decision-making process of aircraft programs. These include examples of business plans for a 50-seat and 78-seat regional jets, description of design phases, market strategy, competition among manufacturers, regulatory requirements, and technology assessment.

Readers will also be introduced to modern methodologies used in the conceptual design process of transport airplanes, such as configuration study, aerodynamics, flight stability and control, performance, certification requirements and the role of flight operations. Thus, the design process is explained in an integrated manner which paves the way towards a better understanding of an optimized aeronautical design environment where noise and emission constraints are taken into consideration.

Conceptual Design of Green Transport Airplanes is an essential reference work for aeronautical engineering students and technicians as well as industry professionals involved in the aviation and environmental protection/regulation industry.

Congenital Toxoplasmosis in Humans and Domestic Animals presents information about Toxoplasma gondii and its infection in neonates and different animals (cats, cattle, dogs, goats, pigs and sheep). Readers will have quick access to the pathophysiology, diagnosis, reproductive disorders (such as abortion, neonatal mortality and prematurity) and treatment of both human and veterinary toxoplasmosis. In addition, important aspects for control programs of congenital toxoplasmosis and for maternal and neonatal screening in such control programs are discussed. Thus readers will be better equipped to conduct prevention programmes and routine diagnosis of zoonotic infections related to T. gondii. This handbook is of interest to epidemiologists, doctors, veterinarians and public health specialists.

Obtaining proper patient consent in clinical care is vital in current times. The approach of 'doctor knows best' is now superseded by patient rights to make decisions. The approach of this book from the author's experience of 13 years in Clinical Risk Management with a special interest in generic consent is to combine different disciplines into a more unified approach that reflects every day practice, rather than citing individual examples of law case studies. By analyzing the elements of these different disciplines a more logical, practical and synergistic approach to consent is achieved. This book differs from others in that the principle elements are combined into one text. The book should help professional and trainee clinicians to acquire a wider understanding of the fundamental principles of medical law, ethics and risk management and their combined role in many situations, particularly in the NHS.

This reference provides information about recent trends in bryology in parts of India, tropical rainforests and arctic regions. Bryophytes are the earliest land plants and quite fascinating in their overall diversity. All through its history, bryological study has contributed considerably to the field of plant sciences, for instance, the discovery of sex chromosomes in plants. The study of bryophytes is fundamental to our understanding of land plant evolution, and the latest progress in molecular phylogenetics and genomics have given researchers a clear depiction of land colonization of plants and subsequent terrestrial progression. Ecologically, the importance of bryophytes for the participation in biogeochemical cycles, in particular carbon cycle is now appreciated. Further, there has been an escalating interest in the conservation biology of bryophytes.

The contributors have put forward holistic information regarding current research scenario of bryology in a range of environments to readers learning about research in applied bryology. The compilation of reviews presents reported findings related to various aspects of the subject, such as, conservation, diversity, tissue culture, bio-monitoring, computational bryology, molecular bryology, and species.

Botanists and bryologists will receive updated information that will be valuable for their research work. The reader-friendly text is also suitable for beginners in applied plant science.

Recent Advances in Botanical Science provides updated research and reviews on topics related to plant biology, genetics, taxonomy and ecology. The series is a useful resource for readers interested in applied plant science.

Contemporary Sleep Medicine should be of interest to a large number of readers interested in sleep medicine. It is divided into two parts – one for patients or simple readers and another for physicians or advanced readers. The Ebook explores new research grounds for sleep disorders. These include novel methodologies for epidemiological research and strategies for curing individuals who suffer from sleep disorders. The volumes seek to update interested readers on the latest advances in the uncharted territory of sleep medicine.

Plasticity in insulin-producing cells (β-cells) of the pancreas is a major contributor to metabolic control. Targeted regeneration of pancreatic β-cells for the reversal of diabetes (by optimizing β-cells mass and proliferation to meet metabolic requirements and counter autoimmune response) is still a theoretical intervention. This monograph reviews the biology, ontogeny, capabilities, and present practical limitations of β-cell plasticity. Relevant biochemical pathways are described with the inclusion of information about how they change with aging, during pregnancy, and with diet. Readers will learn the following key aspects about β-cell plasticity:

-current knowledge of pancreatic β-cells development, and how β-cell mass and proliferation change throughout the human lifespan

-the mechanisms responsible for β-cell plasticity, based on animal models and clinical studies revealing environmental, epigenetic, endocrine and paracrine regulators

-the therapeutic potential of resident stem cells within the pancreas / bone marrow and β-cell progenitors

This monograph is essential reading for researchers interested in updated knowledge about the molecular and cellular biology of β-cells in the quest to find a reliable therapy for diabetes.

In this book volume-2 proposal has been classified into Part IV: Models for SARS-CoV-2 and Part V: Treatment Strategies for SARS-CoV-2. With the emergence of new coronavirus variants, epidemiology, different host tropism permits a thorough analysis of their evolution and acquired adaptability to their host which need different animal models and treatment approaches. No studies are complete without animal models closely related to human physiology to replicate the disease and observe the pathology conditions as in human cases. Such animal models play a vital role in virus pathogenesis and prepare a therapeutic immune response. Here describe bio-engineered transgenic mouse model inserting with specific genes, or CRISPR-Case9 gene-editing tool has been used previously for SARS-CoV and MERS-CoV. The chapter will deal with culture techniques or cell lines for COVID-19—also histopathology of COVID-19, essential proteins that up or down-regulate SARS-CoV-2. The last chapter of this part will describe other diseases having similar signs and symptoms and their differentiation. There is no specific treatment available to date, just symptomatic therapy. However, scientists will elucidate effective antiviral drugs in clinical trials, phytochemicals, photomedicine such as ultraviolet A & B, homemade remedies, blood plasma transfusion, stem cell therapy, and computational approaches in vivo and in vitro trials. This book will appear as a baseline for academicians, scientists, and health professionals as still, research is going to overcome this outbreak of COVID-19, the novelty of best animal models, and find an effective treatment. However, just a single book proposal like this wouldn't have flourished without enthusiasm and determined publishers' and investigators' strength to take time from their busy schedule and subsidize on time. We thank the whole investigators who contributed, directly and indirectly, to bring it to reality.

In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential and vital. Reports as of 20th April 2021 indicate over 141 million cases of SARS-CoV-2 infection worldwide (with over 3 million deaths recorded). This volume brings together essential data regarding prevention (vaccination), detection, and various approaches (chemotherapeutic drugs and antibodies) to the potential treatment of coronavirus infections. It presents six chapters concerning the following topics:

(1) the resistance to the spread of SARS-CoV-2 and related Covid-19 diseases within a population based on the pre-existing immunity of a high proportion of individuals as a result infection or previous vaccination

(2) the impact of the Covid-19 pandemic for the South Asian Association for Regional Cooperation (SAARC) region, comprising the Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka, India, and Afghanistan

(3) the effect of candidate drugs chloroquine and hydroxychloroquine on QT interval in infected patients with Covid-19 diseases

(4) the antiviral potential of herbal-based immunomodulators

(5) the humoral immune response in humans based on anti-SARS-CoV-2 antibodies to treat Covid-19 diseases

(6) the various methods and strategies for diagnosing SARS-CoV-2 (and its variants) infection in hosts/humans.

This compilation should prove to be a tool of crucial importance for researchers around the world working on research revolving around coronaviruses, as well as for clinicians confronted by a growing number of patients with COVID-19.

[Series Introduction]

Coronaviruses presents compilations of reviews which present information about coronaviridae. Volumes in the series present interesting data on the virology, molecular biology, pathogenesis and epidemiology of these viruses. Current topics such as SARS-CoV-2 infection, COVID-19 epidemiology, economic impact of COVID-19, and new coronavirus variants are also included. The series should prove to be an essential resource on this group of viruses for multidisciplinary researchers and healthcare professionals alike.