Bentham Science Publishers

Modern techniques have been developed to overcome problems associated with the extraction of natural products from plants. These techniques include production of secondary metabolites by biotechnological methods such as plant tissue culture and microbial biotransformation of natural substances. Such methods have led to an increased yield of secondary metabolite amount, the discovery of new biochemical derivatives and agricultural development. For instance, use of these techniques in agricultural area have led to some beneficial traits such as formation of new varieties of known plant species, better crop quality, higher yield, better nutritive properties, more resistant species to insects and pests. Microbial biotransformation is beneficial in plant secondary metabolite production and derivatization (chemical modification of any compound made by a microorganism) and is chiefly applicable to several varieties of terpenes and steroids. This E-book demonstrates recent developments in this field. It will be of particular interest to the professionals in pharmaceutical and biotechnological industries, as well as natural product chemists, medicinal chemists, plant biochemists, and molecular biologists.

Continuous efforts to develop new semiconductor devices enable device manufacturers to make significant improvements in the information technology sector. Bipolar transistors and MOSFETS are two special electronic device components that are used to construct very large scale integrated (VLSI) circuits, allowing engineers to create powerful machines that are power efficient. VLSI device characterization depends largely on semiconductor device modeling which is based on physical and electronic principles. Bipolar transistor and MOSFET device models is a textbook that describes basic functions and characterization models of these two types of transistors. Readers will learn about the processes employed to derive these models which will help them understand the modeling process. Chapters in this text cover the fundamentals of semiconductor devices, the pn junction, high and low injection region models for bipolar transistors, and different MOSFET models such as channel doping models and gated SOI models. Key features of this book include:

- step by step, easy to understand presentation of model information on innovative semiconductor devices

- an overview of model derivation, assumptions, approximations and limitations

- novel experimental information on semiconductor parameters such as gate fringe capacitance, silicided source/drain resistance, and threshold voltage shift

Bipolar transistor and MOSFET device models is an essential learning resource for advanced students and professional engineers involved in semiconductor device modeling and fabrication divisions.

Applications of Blockchain in Cybersecurity Solutions is a comprehensive guide to blockchain applications in computer security. it presents the concepts and practical techniques that are useful in creating and designing decentralized cybersecurity software through 9 carefully edited chapters. Topics covered in the book include - An introduction to the use of blockchain technology in cybersecurity - Attack surfaces in blockchains - Anti-counterfeit solutions in blockchains - blockchain based access control systems - Multi-chain security deployment over smart contracts - Cybersecurity as a decentralized service The book is an essential primer for computer science students and researchers, and a quick reference for IT professionals on blockchain based cybersecurity.

New technologies like blockchain and Internet of Things (IoT) are constantly improving the state-of-the-art in healthcare services. The trend of keeping medical records in digital formats is also increasing the reliance of modern healthcare service providers on these new technologies. This edited book brings a collection of reviews on blockchain and IoT technologies that are driving innovation in digital and smart healthcare systems. The editors bring an academic and practical approach to assist professionals and readers in understanding computerized healthcare solutions. 16 referenced chapters provide knowledge about fundamental framework, research insights, and empirical evidence for effective smart healthcare applications. The chapters also cover benefits and challenges of specific smart health frameworks, giving an informative overview of the subject.

Key themes of the book include:

1. Technological Foundations for Smart Healthcare

2. Blockchain Applications in Healthcare

3. Internet of Things (IoT) in Healthcare

4. Artificial Intelligence (AI) Integration

5. Security, Privacy, and Authentication

6. Medical Imaging and Deep Learning

7. Telemedicine

The content in the book is designed to help administrators and healthcare professionals to understand the basics of blockchain tech and IoT in smart healthcare systems and strengthen the competitive advantage of their clinics.

Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease is an update on the recent advances in the development of antioxidant-based therapies. It starts with an overview of the mechanisms underlying the genesis of oxidative stress, summarizing the link between oxidative stress and a number of cardiovascular conditions. This is followed by an explanation of how oxidative stress interacts with lipid metabolism and the placental environment. Three chapters on the role of antioxidant-based therapy for cardiovascular diseases round up the book.

Key Features

- Outlines several cell-signaling pathways that are modulated by the interplay between reducing and oxidizing agents (redox status) and gene expression in the cardiovascular disease process

Brings information about maternal programming environment in the placenta

- Covers development of novel nanotechnology-based antioxidant delivery systems for effective drug delivery

- Includes references for further reading

The book is aimed at a broad readership of scientific and medical professionals involved in research on cardiovascular diseases, pathophysiology, pharmacy, pharmaceutical science and life sciences. It also serves as a reference for scholars who want to understand the complex biochemical mechanisms of antioxidant agents.

This reference presents insights into the development of bone marrow aspirate stem cell (BMAC) technology and the potential role of stem cell expansion in the regeneration of damaged and deficient musculoskeletal tissues. The book features valuable contributions from stem cell therapy experts from around the world. The authors explain the production, proliferation, differentiation into various tissues, and medical applications of stem cells. In addition to work on the use of stem cells in the treatment of non-unions and bone defects, the book explores the potential for articular cartilage regeneration, repair of tendon injuries, the treatment of degenerative joint disease, revascularization of bone and regeneration of damaged nerves as well as spinal cord injury. The authors also explain ethical challenges faced by researchers and public authorities working on stem cells and the varying constraints on the development of this technology around the world.

Scientists and surgeons, alike, who are involved in the fields of orthopaedics, rheumatology, stem cell and regenerative medicine will benefit from the illuminating snapshot of the applications of BMAC stem cell expansion presented in the volume.

Bentham Briefs in Biomedicine and Pharmacotherapy showcases the latest developments and techniques in the fields of pharmacology and healthcare, presenting them in distinctive volumes. Each volume offers a concise, focused overview of subjects, authored by experts in the field. The book series serves as an anthology for graduate students and researchers in pharmacology and life sciences, as well as medical professionals seeking specialization for research-related projects.

The second volume, Botanicals and Natural Bioactives: Prevention and Treatment of Diseases, discusses the medicinal applications of natural bioactives in the treatment of a variety of physiological disorders, including cardiovascular diseases, neurological dysfunctions, infectious diseases, age-related diseases, and cancer. The volume has eight chapters on disease treatment and preventative measures, with contributions from more than twenty experts. Readers will comprehend the niche utilization of botanicals and natural bioactives as medicinal agents for a variety of ailments. Overall, the chapters dwell on the chemosensory features of nutritious foods to avoid non-communicable diseases and the role of immunomodulating natural products and botanicals in the prevention and treatment of skin diseases, aging, inflammation, cancer, parasitic infections in the bloodstream, neurodegenerative diseases, osteoporosis, coronary heart disease, and autoimmune disorders. The variety of topics covered in this book makes it an excellent resource for a wide audience interested in phytomedicine.

Stroke is thought to be the second biggest killer worldwide, and is responsible for over 5 million deaths per year. Several strategies have been developed to enhance treatment of stroke patients. Multimodal neuroimaging allows physicians to diagnose and evaluate not only the ischemic core but also the vessel pattern and collateral status. Stroke Treatment involves extensive intravenous drug administration. Several new drugs with long lasting efficacy are now being tested in randomized clinical trials. In this context, endovascular treatment is a promising avenue that allows physicians to treat patients in extended time windows especially patients in whom intravenous RTPA has failed. A new era has emerged with new devices called stent retrievers and aspiration techniques, which have demonstrated higher rates of recanalization and clear superiority over previous devices employed in RCTs.

The third volume of Frontiers in Neurosurgery presents updated information on ischemic stroke treatment. The volume comprehensively covers the epidemiology, physiology, diagnosis and treatment modalities of stroke. Readers will also find key information on diagnosing and treating rare and lesser known causes of stroke as well as notes about new devices and medical procedures to combat ischemic stroke. This volume is a useful resource for neurosurgery specialists as well as nurses, physiotherapists and caregivers.

Brassinosteroids: Practical Applications in Agriculture and Human Health provides a comprehensive overview on the practical applications of brassinosteroids (BRs) in plant biology (including stress tolerance, growth and development) and human health (anticancer, antiviral and anti-inflammatory activity). The book assures readers a high-quality review of practical applications with a selection of contributions from an international panel of expert researchers. The book suggests new opportunities for professionals to effectively increase the supply of quality food and other plant-derived products, and to improve human health. This book is a reference guide for the performance and interpretation of applications of brassinosteroids to agronomists, chemists, physicians and plant physiologists.

Bridges' Dynamics covers the historical review of research and introductory mathematical concepts related to the structural dynamics of bridges. The e-book explains the theory behind engineering aspects such as 1) dynamic loadings, 2) mathematical concepts (calculus elements of variations, the d' Alembert principle, Lagrange’s equation, the Hamilton principle, the equations of Heilig, and the δ and H functions), 3) moving loads, 4) bridge support mechanics (one, two and three span beams), 5) Static systems under dynamic loading 6) aero-elasticity, 7) space problems (2D and 3D) and 8) absorb systems (equations governing the behavior of the bridge-absorber system). The e-book is a useful introductory textbook for civil engineers interested in the theory of bridge structures.