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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Proteomic Analysis of Mitochondria in Raji Cells Following Exposure to Radiation: Implications for Radiotherapy Response
- Source: Protein and Peptide Letters, Volume 16, Issue 11, Nov 2009, p. 1350 - 1359
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- 01 Nov 2009
Abstract
Radioresistance represents a major obstacle to a successful outcome for the treatment of non-Hodgkin's lymphoma (NHL). Here we performed a global differential proteome analysis of the mitochondria in Raji cells exposed to radiation. The results showed that 23 differentially expressed proteins were identified. Furthermore, GAPDH, RECQL4, MKI67, and ATAD3B could serve as potential biomarkers of radioresistance.
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