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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Regulation of Endochondral Ossification by Osteogenic Growth Peptide CTerminal Pentapeptide [OGP(10-14)]
- Source: Protein and Peptide Letters, Volume 16, Issue 9, Sep 2009, p. 1074 - 1080
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- 01 Sep 2009
Abstract
In neonatal rat metatarsal organ culture, a bell-shaped dose-related curve in length of mineralized area, increases in the height of proliferative and hypertrophic zones, in the number of hypertrophic chondrocyte and in the amount of Runx2 mRNA, were revealed after treatment with OGP(10-14). We conclude that OGP(10-14) accelerates bone growth.
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