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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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Structural and Functional Diversity Among Eukaryotic Hsp70 Nucleotide Exchange Factors
- Source: Protein and Peptide Letters, Volume 16, Issue 6, Jun 2009, p. 623 - 630
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- 01 Jun 2009
Abstract
Since their recent identification, eukaryotic Hsp70 nucleotide exchange factors (NEFs) have gained increasing interest due to their engagement in vital cellular processes. Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human diseases such as cystic fibrosis or amyloidoses.
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