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- ISSN: 0929-8665
- E-ISSN: 1875-5305
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The Importance of Ch / π Interactions to the Function of Carbohydrate Binding Proteins
- Source: Protein and Peptide Letters, Volume 9, Issue 3, Jun 2002, p. 195 - 209
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- 01 Jun 2002
Abstract
It is suggested that the interactions between the hydrophobic C-H groups of carbohydrate residues and the p-electron systems of aromatic amino-acid residues play an important role in the ligand-recognition function of carbohydrate-binding proteins. This review focuses on our recent structural and functional studies of human lysozyme and hevein-domain type lectins (wheat-germ agglutinin and Ac-AMP2) aimed at understanding how CH / π interactions are involved in the actual binding events.
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