Recent Patents on Nanomedicine - Volume 3, Issue 2, 2013

Cancer is one of the leading causes of morbidity and mortality worldwide. Nanotechnology has offered intriguing potential to significantly improve the existing cancer diagnosis and treatment platforms. Recently, a variety of nanomaterials have emerged as promising tools for cancer therapeutic applications due to their unique structural, optical, magnetic, and electrical properties. The purpose of this review is to sum Read More

Nanotechnology has the potential to have a revolutionary impact on targeted cancer diagnosis and therapy. A major challenge in cancer diagnosis is to be able to non-invasively detect tumors at an early stage for maximum therapeutic benefit. In the development of effective therapeutic approaches, targeting and localized delivery are the key challenges. However, because many anticancer drugs are designed to simply ki Read More

Early detection and treatment of diseases will increase the rate of cancer survival. Improving the performance of current diagnostic assay for cancer is in growing need. Recently, as potential diagnostic tools in the field of oncology, inorganic nanoparticles have received increased attention, which promises the promotion of in vitro cancer diagnosis toward new level of performance. Quantum dots (QDs), gold nanoparticles (A Read More

Numerous efforts in oncological scientific research have revealed many causative facets of leukemia, explaining mechanistic aspects of disease progression at the molecular scale. Reports record over 40,000 new cases of patients afflicted with myeloid and lymphocytic leukemia annually worldwide. Early diagnosis and quick therapy are advantageous in effective treatment. Conventional methods mainly rely on blood cell c Read More

Traditional methods of drug delivery present several drawbacks, mainly due to off-target effects that may originate severe side and toxic effect to healthy tissues. Parallel to the development of novel more effective drugs, particular effort has been dedicated to develop and optimize drug delivery vehicles capable of specifically targeting the required tissue/organ and to deliver the cargo only where and when it is needed. N Read More

The prevalence of new and re-emerging infectious diseases in many developing regions of the world indicates that we urgently need new-generation vaccines. Mucosal vaccine delivery systems have been shown to elicit both mucosal and systemic immune responses for protection against pathogens that mainly infect through mucosal routes. However, the efficacy of such vaccine delivery systems has been limited b Read More

Past few decades have evidenced the extensive multidisciplinary investigation in the field of nanotechnology. Nanomedicines have emerged as promising carriers for delivery of diverse therapeutic molecules to the targeted sites. Owing to their unique physiochemical and optical properties, nanomedicines are used for multifunctional applications like delivery of therapeutic molecules, tumor targeting, imaging, etc. This prese Read More

Some self-assembling peptides form stable β-sheet structures and spontaneously self-assemble into nanofibers in water. To produce a stronger self-assembling peptide gel for use in nanomedicine, including drug delivery and tissue engineering, we designed peptides that formed covalent bonds among each other. We inserted the photolinker phenylalanine azide at the N terminus, center, and C terminus of the peptide monomer, Read More