Skip to content
2000
Volume 11, Issue 5
  • ISSN: 2210-3155
  • E-ISSN: 2210-3163

Abstract

Background: The Lamiaceae (Labiatae) family is one of the most diverse and widespread plant families in terms of ethnomedicine and its medicinal value is based on the concentration of the volatile oil present in it. This family is important for flavor, fragrance and medicinal properties. Many plants belonging to this family have indigenous value. Methods: The essential oil of Plectranthus gerardianus Benth. (Lamiaceae) was analyzed by GC and GC-MS analyses, while the major components were isolated and confirmed by NMR spectroscopy. Results: The oil was found to be rich in oxygenated monoterpenes, which contribute around 62% of the total oil. The major components identified were fenchone (22.90%) and carvenone oxide (16.75%), besides other mono and sesquiterpenoids. The in-vitro antimicrobial activity of essential oil was tested against three gram-negative bacteria including Pasteurella multocida, Escherichia coli, and Salmonella enterica, two gram-positive bacteria namely Staphylococcus aureus and Bacillus subtilis and two fungi namely Candida albicans and Aspergillus flavus. The antimicrobial activity of the oil was also compared to the antimicrobial activity of leaf essential oil of another Himalayan plant namely Nepetacoerulescens. Conclusion: The oil showed in-vitro antimicrobial activity against all the microbial strains and can lessen the ever-growing demand for potentially hazardous antibiotics for treatment.

Loading

Article metrics loading...

/content/journals/npj/10.2174/2210315510999200731183701
2021-10-01
2025-10-23
Loading full text...

Full text loading...

/content/journals/npj/10.2174/2210315510999200731183701
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test