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2000
Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882

Abstract

Background

Coronary artery disease (CAD) is a significant contributor to 50%-70% of cardiac failure cases. Successful reperfusion is linked to improved systolic and diastolic functions.

Aim and Objectives

This study aimed to detect the correlation between ECG parameters (QRS duration and fragmentation, QTc, Tpe, and Tpe / QTc ratio), which were proved to be correlated with improved reperfusion post-PCI and associated with the improvement in systolic and diastolic function.

Methods

This prospective research was performed on 54 ischemic cardiomyopathic cases from March 2019 to September 2022. All patients with Ischemic cardiomyopathy (ICM) and an EF less than 40%, along with viable myocardium determined by Dobutamine stress Echocardiography, underwent Complete revascularization of PCI amenable vessels.

Results

There was a statistically significant positive correlation between the QTc interval and EF% after 1 month (r=0.29) and between the QTc interval and the percentage of improvement in both systolic and diastolic functions (EF& E/é) with a more positive correlation with improvement in EF (r=0.35 and 0.27 respectively). A stronger positive and significant correlation between the percentage of improvement in EF% with both Tpe interval, Tpe/QTc ratio, and QRS duration (r= 0.57, 0.50, and 0.58, respectively) was found. Also, there was a positive significant correlation between the percentage of improvement in E/é with both Tpe interval, Tpe/QTc ratio, and QRS duration (r= 0.37, 0.26, and 0.32 respectively)

Conclusion

ECG parameters are capable of predicting improvement of systolic and diastolic functions in ischemic cardiomyopathic patients as observed by improvement in ejection fraction and E/é after PCI compared to before PCI.

© 2024 The Author(s). Published by Bentham Science Publishers. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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  • Article Type:
    Research Article
Keyword(s): CAD; Diastolic function; Electrocardiographic predictors; ICM; PCI; Systolic function
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