Full text loading...
- ISSN: 1389-5575
- E-ISSN: 1875-5607
-
Oncomirs: From Tumor Biology to Molecularly Targeted Anticancer Strategies
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 1, Jan 2009, p. 70 - 80
-
- 01 Jan 2009
Abstract
Deregulation of microRNA (miRNA) promotes carcinogenesis, as these molecules can act as oncogenes or tumor suppressor genes. Here we provide an overview of miRNA biology, discuss the most recent findings on miRNA and cancer development/progression, and report on how tumor-related miRNAs (oncomirs) are being used to develop novel cancer specific therapeutic approaches.
© Bentham Science Publishers