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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus which causes COVID-19, causes damage to many organ systems because of the presence of receptor Angiotensin-Converting Enzyme 2 (ACE2) in widespread tissues. Its pathogenesis includes viral reproduction, immunopathy, oxidative damage, and pathological cytokine activities, which all contribute to its high morbidity and mortality rates. While there are no specific antiviral drugs, preclinical studies have found ginger to be effective in alleviating inflammation, oxidative stress, and viral infections. Research indicates that ginger could help improve the inflammatory and oxidative stress induced by SARS-CoV-2, thus supporting the treatment of COVID-19. The present review reveals the clinical significance of ginger towards COVID-19 as an adjunct therapy and discusses the therapeutic potential of ginger during the COVID-19 pandemic by merging traditional medicine, molecular and in-vitro studies, and clinical studies.
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