Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells

Tomoe Fukui; Hiroaki Kobayashi; Urara Hasegawa; Toshiyuki Nagasawa; Kazunari Akiyoshi; Isao Ishikawa

doi:10.2174/187231207780363570

ISSN: 1872-3128
E-ISSN: 1874-0758

Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells
Authors: Tomoe Fukui¹, Hiroaki Kobayashi², Urara Hasegawa³, Toshiyuki Nagasawa⁴, Kazunari Akiyoshi⁵ and Isao Ishikawa⁶
View Affiliations Hide Affiliations

¹ Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan. ² Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan. ³ Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan. ⁴ Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan. ⁵ Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan. ⁶ Section of Periodontology,Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549,Japan.
Source: Drug Metabolism Letters, Volume 1, Issue 2, Apr 2007, p. 131 - 135
DOI: https://doi.org/10.2174/187231207780363570
- Available online: 01 Apr 2007

Abstract

Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.

Article metrics loading...

/content/journals/dml/10.2174/187231207780363570

2007-04-01

2025-10-11

From This Site

/content/journals/dml/10.2174/187231207780363570

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/dml/10.2174/187231207780363570

Article Type: Research Article

Keyword(s): intracellular delivery; live cell imaging; nanogel; Periodontal ligament cell; quantum dot

Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells

Abstract

From This Site

Most Read This Month