Drug Metabolism and Bioanalysis Letters publishes letters original research articles mini-reviews thematic issues based on mini-reviews and letters commentaries technical notes and drug clinical trial studies on major advances in all areas of drug metabolism and bioanalysis.

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics toxicokinetics species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; bioactivation; recent developments for the identification of drug metabolites reactive intermediate and glutathione conjugates. LC/MS and other key detection methods including ligand binding assays sample preparation chromatography and separation sciences method development and validation with applications in drug and metabolite assays pharmacokinetic/toxicokinetic assays biomarker assays immunogenicity assays diagnostic assays.