Recent Advancements in the Synthesis and Chemistry of Benzo-fused Nitrogen- and Oxygen-based Bioactive Heterocycles

Since a variety of benzo-fused nitrogen- and oxygen-based bioactive heterocyclic moieties are present in the form of benzoxazinones, spirooxindole-based heterocyclic compounds, coumarinfused heterocyclic compounds, and 2H-indazoles, this review article briefly describes some of the major advancements and developments in the area of 1,4-benzoxazine-3-ones, 1,4-benzoxazin-2- ones, spiropyrrolidine and spiropyrrolizine-based ring compounds, coumarin-fused compounds, benzopyran- fused coumarins and a 2H-indazoles class of bioheterocycles. Thus, keeping in view the medicinal importance of these bioactive benzo-fused heterocycles, special attention has been given to their synthesis as well as medicinal/pharmaceutical properties in detail.