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Abstract

A novel class of nanomaterials known as silver nanoparticles (AgNPs) changes the potential in modern medicine. AgNPs are rapidly gaining significance in therapeutic applications ranging from tissue engineering to drug delivery systems due to their strong antibacterial, anticancer, anti-inflammatory, and wound-healing properties. This review presents a comprehensive analysis of the biomedical potential of AgNPs, physical, chemical and biological features that allow for regulated release mechanisms, improved bioavailability, and selective cellular targeting. Considering their obvious promise, there are significant challenges due to concerns about long-term exposure, toxicity, and regulatory uncertainty. We cover new developments, clinical studies, and safety evaluations, providing a balanced perspective of the advantages and disadvantages of AgNP or drug-based therapies. This review proposes a framework for scientists, physicians, and legislators to harness the full therapeutic power of silver nanoparticles while directing associated risks.

© 2025 The Author(s). Published by Bentham Science Publishers.
This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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Review on Harnessing Silver Nanoparticles for Therapeutic Innovations: A Comprehensive Review on Medical Applications, Safety, and Future Directions
Bentham Science Publishers ; https://doi.org/10.2174/0115680266405632250929122554
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  • Article Type:     Review Article
Keywords: Silver nanoparticles (AgNPs) ; Green synthesis ; Therapeutic innovations ; Nanomedicine toxicity and safety ; Biomedical applications ; Cancer therapy

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