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s Computational Modeling of Dielectrophoretic Microfluidic Channel for Simultaneous Separation of Red Blood Cells and Platelets
- Source: Current Signal Transduction Therapy, Volume 15, Issue 3, Dec 2020, p. 243 - 251
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- 01 Dec 2020
Abstract
Background: In this paper, the design and computational modeling of microfluidic channel capable of separating platelets and Red Blood Cell (RBC) from the other blood cells are proposed. Materials and Methods: Separation based on their sizes is made possible by utilizing negative dielectrophoretic (n-DEP) force in fusion with drag force. An array of 38º angled electrode separated by 70 μm distance is designed within the microchannel and analyzed for non-uniform electric field distribution. Results and Conclusion: The molecule movement within the microchannel under induced electric field is simulated to demonstrate the separation using the particle trajectories module. A numerical study is performed for the calculation of Clausius Mossotti (CM) factor, n-DEP force and drag force.