s Yoga may Prevent Cytokine Storm in COVID-19

The pandemic outbreak of coronavirus disease (COVID-19) has emerged as the most threatening public health challenge. The clinical presentation ranges from asymptomatic and mild clinical symptoms to acute respiratory-distress syndrome (ARDS) and death. Apart from the respiratory system, other organ systems like cardiovascular, renal, and gastrointestinal systems are also involved. Cytokine storm is a condition of systemic inflammatory cytokine rampage through the bloodstream leading to lifethreatening complications. There is an urgent need for the prevention of infection and effective management. Yoga is a profound science with both immunity-boosting and immune-modulating capacity. We propose that yoga-based intervention may aid in improving health with its immunity-boosting potential and preventing the exuberant inflammatory cytokine storm, thus reducing the severity of the disease. It can also reduce stress, anxiety, and co-morbid depression by promoting neuroplasticity and prevents persistent activation of the hypothalamus pituitary adrenal axis and thus may reduce disease severity. It may also enhance the immunity of caretakers and make them more emotionally resilient. Thus, yoga can be useful for enhancing immunity, stress reduction and may prevent the exaggerated immune response to the cytokine storm.