Skip to content
2000
Volume 7, Issue 1
  • ISSN: 2666-7967
  • E-ISSN: 2666-7975

Abstract

COVID-19 is the disease, caused by the virus accountable for the latest global pandemic, has caused millions of mortalities and morbidities since its initial spread in 2019, originating in Wuhan, China. The virus is thought to have originated from an animal coronavirus before acquiring the capability of human-to-human transmission and causes acute respiratory syndrome. The virus also presents as a multi-systemic disorder with diverse manifestations across various bodily systems. Over time, we have observed both short-term and long-term complications arising from it. Oral manifestations, particularly uvulitis, have been less studied compared to other symptoms of COVID-19. There is a need for further research to enhance our knowledge about rare symptoms.

© 2026 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/covid/10.2174/0126667975333101240924063620
2024-10-04
2026-03-02

  • From This Site

    /content/journals/covid/10.2174/0126667975333101240924063620
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. MehraeenE. OliaeiS. COVID-19 in pediatrics: A systematic review of current knowledge and practice.Infect. Disord. Drug Targets2022225e290921196908
     [Google Scholar]
  2. SeyedAlinaghiS KarimiA BarzegaryA COVID-19 mortality in patients with immunodeficiency and its predictors: A systematic review.Eur. J. Med. Res.202227119510.1186/s40001‑022‑00824‑736209202
     [Google Scholar]
  3. LiuY.C. KuoR.L. ShihS.R. COVID-19: The first documented coronavirus pandemic in history.Biomed. J.202043432833310.1016/j.bj.2020.04.00732387617
     [Google Scholar]
  4. DalyJ. BlackE.A.M. The impact of COVID-19 on population oral health.Community Dent. Health2020374236238[PMID: 33269826
     [Google Scholar]
  5. MallahS.I. GhorabO.K. Al-SalmiS. COVID-19: breaking down a global health crisis.Ann. Clin. Microbiol. Antimicrob.20212013510.1186/s12941‑021‑00438‑734006330
     [Google Scholar]
  6. MehraeenE. DadrasO. AfsahiA.M. Vaccines for COVID-19: A systematic review of feasibility and effectiveness.Infect. Disord. Drug Targets2022222e23092119675810.2174/187152652166621092314483734554905
     [Google Scholar]
  7. SeyedAlinaghiS MirzapourP PashaeiZ The impacts of COVID-19 pandemic on service delivery and treatment outcomes in people living with HIV: A systematic review.AIDS Res. Ther.2023201410.1186/s12981‑022‑00496‑736609313
     [Google Scholar]
  8. SeyedA. KarimiA. ShobeiriP. Psychological symptoms of COVID-19 epidemic: A systematic review of current evidence.Psihologija (Beogr.)202154217319210.2298/PSI200703035S
     [Google Scholar]
  9. DadrasO SeyedAlinaghiS KarimiA Public acceptability of COVID-19 vaccines and its predictors in Middle ‎Eastern/North African (MENA) countries: A systematic review‎.Hum. Vaccin. Immunother.2022185204371910.1080/21645515.2022.204371935318872
     [Google Scholar]
  10. PoudelA.N. ZhuS. CooperN. Impact of COVID-19 on health-related quality of life of patients: A structured review.PLoS One20211610e025916410.1371/journal.pone.025916434710173
     [Google Scholar]
  11. HaileamlakA. The impact of COVID-19 on health and health systems.Ethiop. J. Health Sci.202131610731074[PMID: 35392335
     [Google Scholar]
  12. AshiqueS. MishraN. MohantoS. Application of artificial intelligence (AI) to control COVID-19 pandemic: Current status and future prospects.Heliyon2024104e2575410.1016/j.heliyon.2024.e2575438370192
     [Google Scholar]
  13. MehraeenE. AfzalianA. AfsahiA.M. Hearing loss and COVID-19: An umbrella review.Eur. Arch. Otorhinolaryngol.202328083515352810.1007/s00405‑023‑07982‑237093291
     [Google Scholar]
  14. SeyedAlinaghiS AfsahiAM ShahidiR Social stigma during COVID-19: A systematic review.SAGE Open Med.2023112050312123120827310.1177/2050312123120827338020797
     [Google Scholar]
  15. SeyedAlinaghiS MehraeenE AfzalianA Ocular manifestations of COVID-19: A systematic review of current evidence.Prev. Med. Rep.20243810260810.1016/j.pmedr.2024.10260838375172
     [Google Scholar]
  16. LiJ. FongD.Y.T. LokK.Y.W. Global impacts of COVID-19 on lifestyles and health and preparation preferences: An international survey of 30 countries.J. Glob. Health2023130603110.7189/jogh.13.0603137565394
     [Google Scholar]
  17. NaveedN. AhmadK. MajeedH. The global impact of covid-19: A comprehensive analysis of its effects on various aspects of life.Toxicol. Res.2024132tfae04510.1093/toxres/tfae04538545435
     [Google Scholar]
  18. ElrobaaI.H. NewK.J. COVID-19: Pulmonary and extra pulmonary manifestations.Front. Public Health2021971161610.3389/fpubh.2021.71161634650947
     [Google Scholar]
  19. LouisT.J. QasemA. AbdelliL.S. NaserS.A. Extra-pulmonary complications in SARS-CoV-2 infection: A comprehensive multi organ-system review.Microorganisms202210115310.3390/microorganisms1001015335056603
     [Google Scholar]
  20. Gracia-RamosA.E. Martin-NaresE. Hernández-MolinaG. New onset of autoimmune diseases following COVID-19 diagnosis.Cells20211012359210.3390/cells1012359234944099
     [Google Scholar]
  21. FaiyazuddinM. SophiaA. AshiqueS. Virulence traits and novel drug delivery strategies for mucormycosis post-COVID-19: A comprehensive review.Front. Immunol.202314126450210.3389/fimmu.2023.126450237818370
     [Google Scholar]
  22. IranmaneshB. KhaliliM. AmiriR. ZartabH. AflatoonianM. Oral manifestations of COVID ‐19 disease: A review article.Dermatol. Ther.2021341e1457810.1111/dth.1457833236823
     [Google Scholar]
  23. Cuevas-GonzalezM.V. Espinosa-CristóbalL.F. Donohue-CornejoA. COVID-19 and its manifestations in the oral cavity.Medicine (Baltimore)202110051e2832710.1097/MD.000000000002832734941133
     [Google Scholar]
  24. RatheeM. JainP. AgeusiaStatPearls. Treasure Island, FLStatPearls Publishing2024Internet
     [Google Scholar]
  25. Welge-LüssenA. GudziolH. Etiology, diagnostic and therapeutic management of taste disorders.Ther. Umsch.2004615302307[PMID: 15195715
     [Google Scholar]
  26. FaridH. KhanM. JamalS. GhafoorR. Oral manifestations of COVID‐19‐A literature review.Rev. Med. Virol.2022321e224810.1002/rmv.224834028129
     [Google Scholar]
  27. Chaux-BodardA.G. DeneuveS. DesoutterA. Oral manifestation of COVID-19 as an inaugural symptom?J Oral Med Oral Surg20202621810.1051/mbcb/2020011
     [Google Scholar]
  28. FaviaG. TempestaA. BarileG. COVID-19 symptomatic patients with oral lesions: clinical and histopathological study on 123 cases of the university hospital policlinic of bari with a purpose of a new classification.J. Clin. Med.202110475710.3390/jcm1004075733668602
     [Google Scholar]
  29. Martín Carreras-PresasC. Amaro SánchezJ. López-SánchezA.F. Jané-SalasE. Somacarrera PérezM.L. Oral vesiculobullous lesions associated with SARS-CoV-2 infection.Oral Dis.202127Suppl. 3710712
     [Google Scholar]
  30. Amorim dos SantosJ. NormandoA.G.C. Carvalho da SilvaR.L. Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations?Int. J. Infect. Dis.20209732632810.1016/j.ijid.2020.06.01232526392
     [Google Scholar]
  31. LaskeyW. AwadK. LumJ. An analysis of implantable cardiac device reliability. The case for improved postmarketing risk assessment and surveillance.Am. J. Ther.201219424825410.1097/MJT.0b013e3182512ca522668602
     [Google Scholar]
  32. Jimenez-CauheJ. Ortega-QuijanoD. Carretero-BarrioI. Erythema multiforme‐like eruption in patients with COVID‐19 infection: clinical and histological findings.Clin. Exp. Dermatol.202045789289510.1111/ced.1428132385858
     [Google Scholar]
  33. WollinaU. KaradağA.S. Rowland-PayneC. ChiriacA. LottiT. Cutaneous signs in COVID ‐19 patients: A review.Dermatol. Ther.2020335e1354910.1111/dth.1354932390279
     [Google Scholar]
  34. BiadseeA. BiadseeA. KassemF. DaganO. MasarwaS. OrmianerZ. Olfactory and oral manifestations of COVID‐19: Sex‐related symptoms—A potential pathway to early diagnosis.Otolaryngol. Head Neck Surg.2020163472272810.1177/019459982093438032539587
     [Google Scholar]
  35. HedouM. CarsuzaaF. CharyE. HainautE. Cazenave-RoblotF. RegnaultM.M. Comment on ‘Cutaneous manifestations in COVID‐19: A first perspective’ by Recalcati S.J. Eur. Acad. Dermatol. Venereol.2020347e299e30010.1111/jdv.1651932314436
     [Google Scholar]
  36. PatelJ. WoolleyJ. Necrotizing periodontal disease: Oral manifestation of COVID-19.Oral Dis.202127Suppl. 3768769
     [Google Scholar]
  37. AshiqueS. MishraN. GargA. A critical review on the long-term COVID-19 impacts on patients with diabetes.Am. J. Med.2025138230832910.1016/j.amjmed.2024.02.02938485111
     [Google Scholar]
  38. LathadeviH.T. KaradiR.N. ThobbiR.V. GuggarigoudarS.P. KulkarniN.H. Isolated uvulitis: An uncommon but not a rare clinical entity.Indian J. Otolaryngol.200557213914010.1007/BF0290766923120151
     [Google Scholar]
  39. CohenM. ChhetriD.K. HeadC. Isolated uvulitis.Ear Nose Throat J.200786846246410.1177/01455613070860081017915667
     [Google Scholar]
  40. YadavY. HafeezD. AcharyaS. MacQueenD. GuptaS.S. Acute uvulitis in COVID-19 patient: A rare yet worrisome symptom!Chest20231644A623410.1016/j.chest.2023.07.4011
     [Google Scholar]
  41. AhmadiA JamaliM SanaeiA Acute isolated uvula swelling: A rare manifestation in patients with COVID-19.Razi J Med Sci20212711fa83fa89
     [Google Scholar]
/content/journals/covid/10.2174/0126667975333101240924063620
Loading

  • Article Type:     Review Article
Keyword(s): morbidities; mortalities; multi-systemic; Respiratory syndrome; uvulitis; virus

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test