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2000
Volume 6, Issue 4
  • ISSN: 2666-7967
  • E-ISSN: 2666-7975

Abstract

Objectives

This work aimed to study the difference in the level of fatigue perception between cases and controls, who did not have COVID-19. This study sought to establish the impact of severity of infection with fatigue scores on the quality of life.

Methods

This observational case-control study, recruiting 165 participants, both males and females, from Fazaia Ruth Pfau Medical College, Karachi, Pakistan, started from August 2022 to October 2023 after obtaining their consent. A total of 65 COVID-positive with 21.5% hospitalized and 78.5% non-hospitalized subjects were included. Post-COVID fatigue among the participants was compared using the validated Fatigue Severity Scale (FSS), Chalder Fatigue Scale (CFQ-11), and WHOQOL scale.

Results

Participants in all groups reported fatigue on the Fatigue Severity Scale with COVID-positive (38.25 ±12.15) and Covid-negative (33.75±11.28) rate, with a significant -value (0.031). According to CFQ, no significant difference ( = 0.91) was found between fatigue scores of Covid positive and negative. However, a significant ( = 0. 016) difference was observed between Covid-positive hospitalized (4.37±0.33) and non-hospitalized (1.98 ±0.22) subjects. QOL scores in different domains, including QOL General Health (7.18±1.54), physical (20.38±3.51), psychological (46.33±7.05), and social (9.98±1.94), were all significant ( = 0.00) when compared between Covid positives and negatives.

Conclusion

The study revealed that post-covid survivors experienced fatigue, which imposed limitations on different aspects of life, which was different from the fatigue of non-affected individuals.

© 2025 Bentham Science Publishers
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2024-07-05
2025-10-03

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/content/journals/covid/10.2174/0126667975301718240625111222
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A Comparative Study to Assess Post-COVID Fatigue and its Functional Limitations
Coronaviruses 6, E050724231648 (2025); https://doi.org/10.2174/0126667975301718240625111222
/content/journals/covid/10.2174/0126667975301718240625111222
/content/journals/covid/10.2174/0126667975301718240625111222
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  • Article Type:     Research Article
Keyword(s): chalder fatigue scale; COVID-19; fatigue severity scale; morbidity; mortality; SARS-CoV-2; WHOQOL scale

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