Ionic Liquid Supported Organocatalysts for the Asymmetric Mannich- Type Reaction of α-cyano α-sulfonyl Carbanions

Introduction: We synthesized proline functionalized ionic liquid and further characterized it with analytical techniques. Method: After getting proper structural information on the above ionic liquid, we utilized them as a catalyst for the asymmetric Mannich-Type Reaction. Result: We synthesized 6 different types of β-amino α-cyano sulfones derivatives as Mannich adduct using various combinations of different imines and aryl sulphonyl as pre-nucleophiles. Conclusion: We obtained the corresponding chiral Mannich adduct followed by simple ether washing in excellent yield and stereoselectivity. We recycled the catalyst up to 6 runs without losing the catalytic activity.