The Effect of Lewis Acid Catalysis and Steric Effects on Reactions of Tin Hydrides

The catalytic influence of inorganic salts, polarity of solvent and addition of chosen additivities on free radical reactions of tin hydrides has been reviewed. There have been collected examples of different reactions as hydrostannation of alkynes with mixed tin hydrides as well as enantioselective reductions of derivatives of 2-bromo-2-arylpropionates, α-iodocoumarin and acetophenone with tin hydrides. For all of them the steric effect may be improved by the addition of inorganic salts. They have been discussed examples of tandem radical macrocyclisations and reactions of α-amide radicals depending on polarity of solvent. They have been also presented examples of hydrostannation of methylenecycloprpanes effected by the addition of additivities.