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image of A Comprehensive Review on Garlic Oil as an Anti-inflammatory Nanoemulsion

Abstract

Although garlic oil is well known for its medicinal benefits, its low solubility and lipophilic characteristics result in restricted bioavailability. The goal of this work was to create a stable nanoemulsion technology that would increase the anti-inflammatory properties of garlic oil. Particle size, stability, zeta potential, and polydispersity index were used to characterize the nanoemulsion. and models were used to assess the formulated nanoemulsion's anti-inflammatory properties. The findings showed that, in comparison to refined oil, the garlic oil nanoemulsion had a noticeably stronger anti-inflammatory effect. The nanoemulsion showed less gastrointestinal discomfort, extended activity, and enhanced absorption. According to these results, garlic oil nanoemulsion shows promise as a possible treatment for inflammatory diseases. By creating a nanoemulsion using essential oil of garlic (GEO), the volatile components of garlic oil have been effectively encapsulated and protected by experts. The components in garlic oil are more stable because of this encapsulation process, which also increases the ability of the body to absorb and use them. For people taking garlic oil as a supplement or functional ingredient, the enhanced bioavailability of garlic oil constituents through nanoemulsion may result in greater effectiveness and health advantages. This improved stability helps keep the components in garlic oil from oxidizing and degrading, guaranteeing their quality and effectiveness throughout time. Nanoemulsion provides a workable way to add garlic oil to a variety of goods without sacrificing its efficacy by prolonging the shelf life of garlic oil constituents. Garlic oil nanoemulsion has prospective uses in the food, pharmaceutical, and agricultural sectors, among others.

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/content/journals/cnanom/10.2174/0124681873351720241218103730
2025-01-23
2025-09-04

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/content/journals/cnanom/10.2174/0124681873351720241218103730
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  • Article Type:     Review Article
Keywords: essential oil ; nanoemulsion ; garlic oil ; Anti-inflammatory activity ; homogenization

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