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Flower-like ZnO nanostructures had been successfully synthesized by solvothermal treatment of a precursor 4,5-diphenyloxazole- 2-propanoic acid-zinc (abbreviated as oxaprozin-Zn) complex without using any surfactants. The influence of basicity, temperature, and reaction time on the formation of such structures was investigated. Room-temperature photoluminescence spectrum of welldefined uniform ZnO nanoflowers was investigated. The results indicated that the choice of a precursor could have significant influence on the growth of ZnO nanostructures. This type of complex could be used to prepare other oxdinations with special morphology, suah as CdO and CuO.