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2000
Volume 22, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Introduction

Pseudomyogenic Hemangioendothelioma (PMHE), also known as epithelioid sarcoma-like hemangioendothelioma, is a rare, indolent, low-grade vascular tumor. It typically presents as firm cutaneous nodules, with a predilection for the lower extremities and a male predominance. While numerous cases have been reported in pathology literature, detailed radiologic descriptions, particularly of soft tissue origins, are scarce. This report aims to bridge this gap by presenting a rare case of PMHE with comprehensive imaging findings.

Case Presentation

We report on a 67-year-old male who presented with painful, palpable papules on his right buttock. MRI revealed multifocal dermal nodules demonstrating low signal intensity on T1-weighted images and high signal intensity with a distinctive peripheral high-signal halo on T2-weighted images. Notably, T1 gadolinium fat-saturated sequences exhibited marked enhancement with a characteristic peripheral rim enhancement pattern. The lesions were confined to the cutaneous layer. Initial radiological differentials included post-inflammatory granuloma and sarcoma. Histopathological examination confirmed PMHE. PET/CT demonstrated no evidence of systemic metastasis, and the patient has remained recurrence-free for two years following surgery.

Conclusion

This report highlights a rare case of cutaneous PMHE and details its distinctive MRI features, particularly the peripheral rim enhancement. Given its rarity and often non-specific clinical and imaging presentations, there is a significant potential for misdiagnosis. Therefore, it is crucial for radiologists to be aware of PMHE and familiarize themselves with its characteristic radiological patterns to facilitate accurate, timely diagnosis and ensure appropriate patient management.

© 2026 The Author(s). Published by Bentham Science Publishers.
This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2026-01-30
2026-02-23

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Soft Tissue Pseudomyogenic Hemangioendothelioma in the Buttock: A Case Report
Curr. Med. Imaging 22, E15734056433778 (2026); https://doi.org/10.2174/0115734056433778251217073245
/content/journals/cmir/10.2174/0115734056433778251217073245
/content/journals/cmir/10.2174/0115734056433778251217073245
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  • Article Type:     Case Report
Keyword(s): Epithelioid sarcoma-like hemangioendothelioma; Magnetic resonance imaging; Pseudomyogenic hemangioendothelioma; Soft tissue neoplasm

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