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2000
Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Introduction

An accurate staging diagnosis of rectal cancer holds crucial importance in determining the appropriate treatment plan for patients.

Aim

To evaluate the application of transrectal biplane ultrasonography combined with Sound Touch Elastography (STE) technology in preoperative uT stage of rectal cancer.

Methods

A retrospective analysis was conducted on the ultrasonographic data of 32 patients. The STE values within the tumor and the adjacent peritumoral fat tissue were recorded, and the ratio of STE values between adjacent and distant peritumoral fat tissues was defined as the Stiffness Ratio (SR).

Results

The STE values were not statistically significantly different between the high and low pT stage groups within tumors (P > 0.05). However, there were statistically significant differences in the STE values of the adjacent peritumoral fat tissue and the SR between the two groups ( < 0.05). Binary logistic regression analysis showed that the SR was a relevant factor in distinguishing high and low pT stages of rectal cancer. The optimal cut-off value of the SR was 1.915, with a sensitivity of 95.7% and a specificity of 88.9% in predicting high pT stages of rectal cancer. The consistency observed between traditional TRUS and pathological staging in differentiating between high and low pT stages of rectal cancer was moderate. However, the incorporation of SR had enhanced this consistency to a favorable level.

Conclusion

The combination of TRUS and STE technology enhanced the accuracy of pT stage in rectal cancer, with SR serving as a critical indicator for predicting high pT stages and constituting a valuable supplement to traditional TRUS.

This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2025-06-30
2025-09-20
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References

  1. SiegelR.L. GiaquintoA.N. JemalA. Cancer statistics, 2024.CA Cancer J. Clin.2024741124910.3322/caac.2182038230766
    [Google Scholar]
  2. BensonA.B. VenookA.P. Al-HawaryM.M. AzadN. ChenY.J. CiomborK.K. CohenS. CooperH.S. DemingD. Garrido-LagunaI. GremJ.L. GunnA. HechtJ.R. HoffeS. HubbardJ. HuntS. JeckW. JohungK.L. KirilcukN. KrishnamurthiS. MarattJ.K. MessersmithW.A. MeyerhardtJ. MillerE.D. MulcahyM.F. NurkinS. OvermanM.J. ParikhA. PatelH. PedersenK. SaltzL. SchneiderC. ShibataD. SkibberJ.M. SofocleousC.T. Stotsky-HimelfarbE. TavakkoliA. WillettC.G. GregoryK. GurskiL. Rectal cancer, version 2.2022, NCCN clinical practice guidelines in oncology.J. Natl. Compr. Canc. Netw.202220101139116710.6004/jnccn.2022.005136240850
    [Google Scholar]
  3. YouY.N. HardimanK.M. BaffordA. PoylinV. FranconeT.D. DavisK. PaquetteI.M. SteeleS.R. FeingoldD.L. On Behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons The american society of colon and rectal surgeons clinical practice guidelines for the management of rectal cancer.Dis. Colon Rectum20206391191122210.1097/DCR.000000000000176233216491
    [Google Scholar]
  4. DongX.Y. LiQ.M. XueW.L. SunJ.W. ZhouH. HanY. ZhouX.L. HouX.J. Diagnostic performance of endorectal ultrasound combined with shear wave elastography for rectal tumors staging.Clin. Hemorheol. Microcirc.202384439941110.3233/CH‑23171637334584
    [Google Scholar]
  5. LoftM.K. PedersenM.R.V. GrimmP. LauritzenA.H. DamC. RafaelsenS.R. Intra- and interobserver variability of shear wave elastography in rectal cancer.Cancers20221411263310.3390/cancers1411263335681613
    [Google Scholar]
  6. FanZ. CongY. ZhangZ. LiR. WangS. YanK. Shear wave elastography in rectal cancer staging, compared with endorectal ultrasonography and magnetic resonance imaging.Ultrasound Med. Biol.20194571586159310.1016/j.ultrasmedbio.2019.03.00631085029
    [Google Scholar]
  7. FengY. PengC. ZhuY. LiuL. Biplane transrectal ultrasonography plus ultrasonic elastosonography and contrast-enhanced ultrasonography in T staging of rectal cancer.BMC Cancer202020186210.1186/s12885‑020‑07369‑032894078
    [Google Scholar]
  8. FukuiR. SasakiK. KawaiK. TairaT. NozawaH. KanekoM. MuronoK. EmotoS. IidaY. IshiiH. YokoyamaY. AnzaiH. SonodaH. IshiharaS. Establishing a novel method for assessing elasticity of internal anal sphincter using ultrasonic real-time tissue elastography.ANZ J. Surg.2021916E360E36610.1111/ans.1676033844397
    [Google Scholar]
  9. SushaalC.R. PatilV.M. PatilS. The role of sound touch elastography in assessment of liver fibrosis in chronic liver disease keeping APRI as the reference standard.Abdom. Radiol.202348113373338110.1007/s00261‑023‑04018‑537620709
    [Google Scholar]
  10. WangJ. WuM. LinghuR. ChangJ. WuM. FengC. RenX. LiuC. LinJ. SongT. GuJ. ZhangY. FangY. MaS. HuP. WuL. HanX. ChenK. ShiQ. ZhangR. ZhouQ. DuR. GaoY. JingX. YangS. ZhouC. ZhengJ. LiangP. ZhengR.Q. Usefulness of new shear wave elastography technique for noninvasive assessment of liver fibrosis in patients with chronic hepatitis b: A prospective multicenter study.Ultraschall Med.2022432e1e1010.1055/a‑1376‑673433910257
    [Google Scholar]
  11. YangL. LiJ. MaL. XiangH. HeD. LuC. TangL. LuoY. ChenS. Noninvasive assessment of liver fibrosis in chronic hepatitis B carriers with sound touch elastography: study of surgical pathology specimens.Expert Rev. Med. Devices202017884585310.1080/17434440.2020.179822632686517
    [Google Scholar]
  12. HildebrandtU. FeifelG. Preoperative staging of rectal cancer by intrarectal ultrasound.Diseases of the Colon & Rectum19852814246
    [Google Scholar]
  13. DongB. LyuG. WangH. ChenY. WeiK. Use of sound touch elastography and sound touch quantification for the noninvasive evaluation of portal hypertension in a rat model.J. Ultrasound Med.20234271537154710.1002/jum.1617236637111
    [Google Scholar]
  14. HuangX. ChenX. ChenX. ChiP. WangP. ZhanX. ZouC. WangL. DongY. Sound touch elastography of Achilles tendons in patients with type 2 diabetes mellitus versus healthy adults.Diabetol. Metab. Syndr.202315117410.1186/s13098‑023‑01148‑037599363
    [Google Scholar]
  15. RuanZ. XiaoZ. ShiX. LiangY. HouL. WuT. WuM. Comparison of sound touch elastography and quantification for assessing the renal pathologic changes in patients with proteinuria.Insights Imaging202314113510.1186/s13244‑023‑01476‑937541990
    [Google Scholar]
  16. XiangH. LingW. MaL. YangL. LinT. LuoY. Shear wave elastography using sound touch elastography and supersonic shear imaging for liver measurements: A comparative study.Quant. Imaging Med. Surg.20221252855286510.21037/qims‑21‑86335502377
    [Google Scholar]
  17. ChenL.D. WangW. XuJ.B. ChenJ.H. ZhangX.H. WuH. YeJ.N. LiuJ.Y. NieZ.Q. LuM.D. XieX.Y. Assessment of rectal tumors with shear-wave elastography before surgery: Comparison with endorectal US.Radiology2017285127929210.1148/radiol.201716212828640694
    [Google Scholar]
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