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Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Introduction

Conventional skin tumor examination shows inherent limitations in accurately assessing tumor depth. HR-MRI offers superior soft tissue resolution and a comprehensive evaluation of skin cancer.

Methods

Patients confirmed by pathological diagnosis as non-melanoma skin cancer from January 2021 to December 2023 were enrolled. Patients in Group 1 received both HR-MRI and tumorectomy, while those in Group 2 received tumorectomy only. The exclusion criteria include patients with contraindications to magnetic resonance examination. MRI sequences included T1WI, T2WI, and T2WI fat suppression, and a dynamic contrast-enhanced(DCE) scan. The advantages of different sequences in evaluating the level of invasion were independently assessed by two radiologists. The advantages of different sequences in evaluating the level of invasion were independently assessed by two radiologists. Tumor size, shape, invasion, and dynamic curves were measured in a corresponding sequence. And tumor signal intensity was recorded in different sequences. For each group, the number of postoperative tissue sections, sections with positive margins, and cases of secondary surgery were recorded. For Group 1, pathological invasion levels were also recorded.

Results

89 cases of non-melanoma skin cancer were collected, including 69 basal cell carcinoma (BBC) and 20 squamous cell carcinoma (SCC). There were 25 patients in group 1 and 59 patients in group 2. T1WI showed mainly isointensity or hypointensity for BCC and SCC. T2WI showed predominantly hyperintense, and T2WI with fat suppression all showed hyperintense. T2WI effectively showed the relationship between tumors and nearby structures, while fat-suppressed T2WI highlighted tumor contours. The positive rate of pathological sections and the rate of secondary resection in group 1 and group 2 were 9.7% and 20%, 23.1% and 44.1%. There was a higher consistency between tumor invasion levels observed by MRI and pathological results in the first group (p>0.75)

Discussion

Advancements in skin tumor diagnosis and treatment reveal that some tumors penetrate deeper than traditional methods can detect, prompting interest in MRI research. HR-MRI, known for its excellent soft tissue resolution, proves useful in outlining tumors and determining their location, particularly with the T2 fat-suppressed sequence. The T2WI sequence effectively assesses skin invasion, aligning well with pathological findings, and this significantly reduces the need for subsequent surgical interventions.. This underscores HR-MRI's value as a preoperative tool. However, the study's small sample size is a limitation, and future research will include more cases for deeper insights.

Conclusion

Skin HR-MRI is valuable for non-melanoma skin cancer, providing accurate preoperative tumor scope assessment, and reducing the rate of secondary surgeries.

© The Author(s). Published by Bentham Science Publishers.
This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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Application Value of High Resolution Magnetic Resonance Imaging in Preoperative Evaluation of Non-melanoma Skin Cancer
Curr. Med. Imaging 21, E15734056360576 (2025); https://doi.org/10.2174/0115734056360576250731135230
/content/journals/cmir/10.2174/0115734056360576250731135230
/content/journals/cmir/10.2174/0115734056360576250731135230
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  • Article Type:     Research Article
Keyword(s): Basal cell carcinoma; Cutaneous squamous cell carcinoma; High-resolution magnetic resonance; OCT; Preoperative evaluation; Skin tumor

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