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2000
Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603

Abstract

Background

Chronic Kidney Disease (CKD) affects individuals of different age groups worldwide. Moreover, CKD is associated with several risk factors, including obesity, lifestyle, and hypertension, which are common in the Middle East. Ultrasonography is the examination of choice for CKD. In recent years, Shear Wave Elastography (SWE) has developed through the continued development of ultrasound and received substantial attention ;therefore, it can be used to measure tissue stiffness. The study aimed to use point Shear Wave Elastography (p-SWE) to determine the correlation between diabetes and cortical renal thickness in detecting pathologies.

Methods

This study was performed at the King Abdul-Aziz University Hospital. We examined 61 patients who underwent SWE. The patients were classified into two groups based on the presence or absence of type 2 Diabetes Mellitus (DM).

Results

The results showed that there was a significant correlation between cortical stiffness and DM duration [p<0.005]. In addition, there was a negative correlation between cortical stiffness and cortical thickness [p=0.147] in patients with DM. Moreover, the eGFR decreased with an increase in cortical stiffness [p=0.499]. The cortical thickness in patients with and without DM was 0.750 ± 0.2 kPa and 0.788 ± 0.4 kPa, respectively. The kidney stiffness in patients with DM and control patients was 8.5 ± 8.6 cm and 14.0 ± 25.16 cm, respectively.

Conclusion

This study showed that kidney p-SWE measurements were reliable. Therefore, further studies assessing kidney stiffness in patients with and without people with diabetes are recommended.

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2024-01-01
2025-09-27
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References

  1. AlebiosuC.O. AyodeleO.E. The global burden of chronic kidney disease and the way forward.Ethn Dis.20051523418423
    [Google Scholar]
  2. SirolaJ. RikkonenT. TuppurainenM. HonkanenR. KrögerH. Should risk of bone fragility restrict weight control for other health reasons in postmenopausal women? – A ten year prospective study.Maturitas201271216216810.1016/j.maturitas.2011.11.02022177977
    [Google Scholar]
  3. KoyeD.N. The global epidemiology of diabetes and kidney disease.Advances in Chronic Kidney Disease.W.B. Saunders201812113210.1053/j.ackd.2017.10.011
    [Google Scholar]
  4. LeightonT.G. What is ultrasound?Prog. Biophys. Mol. Biol.2007931-338310.1016/j.pbiomolbio.2006.07.02617045633
    [Google Scholar]
  5. SigristR.M.S. ‘Ultrasound elastography: Review of techniques and clinical applications’, Theranostics.Ivyspring International Publisher20171303132910.7150/thno.18650
    [Google Scholar]
  6. OzturkA. GrajoJ.R. DhyaniM. AnthonyB.W. SamirA.E. Principles of ultrasound elastography.Abdom. Radiol.201843477378510.1007/s00261‑018‑1475‑629487968
    [Google Scholar]
  7. LeeS.M. KimM.J. YoonJ.H. HongW. HaH.I. LeeK. ChoeJ.Y. LeeJ.W. YoonS.Y. HanJ. Comparison of point and 2-dimensional shear wave elastography for the evaluation of liver fibrosis.Ultrasonography202039328829710.14366/usg.1909032311869
    [Google Scholar]
  8. SporeaI. BotaS. Grădinaru-TaşcăuO. ŞirliR. PopescuA. Comparative study between two point shear wave elastographic techniques: Acoustic radiation force impulse (ARFI) elastography and ElastPQ.Med. Ultrason.201416430931410.11152/mu.201.3.2066.164.isp125463883
    [Google Scholar]
  9. HassanK. LoberantN. AbbasN. FadiH. ShadiaH. KhazimK. Shear wave elastography imaging for assessing the chronic pathologic changes in advanced diabetic kidney disease.Ther. Clin. Risk Manag.2016121615162210.2147/TCRM.S11846527853373
    [Google Scholar]
  10. LinH.Y.H. LeeY.L. LinK.D. ChiuY.W. ShinS.J. HwangS.J. ChenH.C. HungC.C. Association of renal elasticity and renal function progression in patients with chronic kidney disease evaluated by real-time ultrasound elastography.Sci. Rep.2017714330310.1038/srep4330328240304
    [Google Scholar]
  11. KocA.S. SumbulH.E. Renal cortical stiffness obtained by shear wave elastography imaging is increased in patients with type 2 diabetes mellitus without diabetic nephropathy.J. Ultrasound201821427928510.1007/s40477‑018‑0315‑430051234
    [Google Scholar]
  12. a LeongS.S. WongJ.H.D. Md ShahM.N. VijayananthanA. JalalonmuhaliM. NgK.H. Shear wave elastography in the evaluation of renal parenchymal stiffness in patients with chronic kidney disease.Br. J. Radiol.20189110892018023510.1259/bjr.2018023529869920
    [Google Scholar]
  13. b KwongR.Y. YucelE.K. Computed tomography scan and magnetic resonance imaging.Circulation200310815e104e10610.1161/01.CIR.0000086899.32832.EC
    [Google Scholar]
  14. KocA.S. Erdem SumbulH. GülümsekE. Increased renal cortical stiffness in patients with advanced diabetic kidney disease.Saudi J Kidney Dis Transpl.2019301138150
    [Google Scholar]
  15. KuttancheriT. KrishnanK. DasS.K. ShettyM.S. Shear wave elastography: Usefulness in chronic kidney disease.Pol. J. Radiol.202388128629310.5114/pjr.2023.12869437404549
    [Google Scholar]
  16. YuksekkayaR. CelikyayF. YuksekkayaM. KutluturkF. Shear wave elastography in early diabetic kidney disease.Rev. Assoc. Med. Bras.2022686765769, 765-76910.1590/1806‑9282.2021104235584435
    [Google Scholar]
  17. AlyamiJ. AlmutairiF.F. AldoassaryS. AlbeshryA. AlmontashriA. AbounassifM. AlamriM. Interobserver variability in ultrasound assessment of thyroid nodules.Medicine202210141e3110610.1097/MD.000000000003110636254067
    [Google Scholar]
  18. AlyamiJ. AlmutairiF. Arterial stiffness assessment in healthy participants using shear wave elastography.Curr. Med. Imaging Rev.202218101086109210.2174/157340561866622041512453535430974
    [Google Scholar]
  19. AlmutairiF.F. Preliminary investigation of normal pancreas elasticity using point shear wave elastography.Curr. Med. Imaging Rev.20231912e10022321358910.2174/157340561966623021015175436809937
    [Google Scholar]
  20. AlmutairiF.F. Measurement variability in two-dimensional shear wave elastography (SWE) of common carotid artery (CCA).Egypt. J. Radiol. Nucl. Med.202253116
    [Google Scholar]
  21. AlmutairiF.F. AbdeenR. AlyamiJ. SultanS.R. Effect of depth on ultrasound point shear wave elastography in an elasticity phantom.Appl. Sci.20221213629510.3390/app12136295
    [Google Scholar]
  22. FangJ.X. ChenX.Y. YangQ.M. XueM.H. Factors influencing renal parenchymal stiffiness in patients with diabetic nephropathy.Int. J. Gen. Med.2021141911191710.2147/IJGM.S31142034040423
    [Google Scholar]
  23. SumbulH.E. KocA.S. DemirtasD. KocaH. PekozB.C. GorguluF.F. DonmezY. DemirtasA.O. KocM. IcenY.K. Increased renal cortical stiffness obtained by share-wave elastography imaging significantly predicts the contrast-induced nephropathy in patients with preserved renal function.J. Ultrasound2019222185191, 185-19110.1007/s40477‑019‑00373‑630877661
    [Google Scholar]
  24. MengF. WuQ. ZhangW. HouS. Shear-wave elastography-based radiomics nomogram for the prediction of cardiovascular disease in patients with diabetic kidney disease.Diabetes Metab. Syndr. Obes.2023162705271610.2147/DMSO.S42236437701720
    [Google Scholar]
  25. WuJ. LiG. LiuJ. SunW. LiuJ. ZouG. ZhengM. Utility of shear wave–based ultrasound elastography in chronic kidney disease and related pathological quantitative analysis.Eur. Radiol.202319
    [Google Scholar]
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