Cardiac Complications in Hypertension and Diabetes: Role of Sympathetic Nervous Activity

Hypertension and diabetes mellitus are closely associated, Cardiovascular complications and organ damages are augmented in hypertensive patients with diabetes mellitus compared to those without diabetes mellitus. The important common worsening factors in diabetes mellitus and essential hypertension are insulin resistance associated with sympathoexcitation. We should consider that sympathoinhibition is a reasonable therapy for the hypertensive patients with diabetes mellitus to prevent cardiovascular complications and organ damages, and that sympathoinhibition could be contributes to improve the survival of the hypertensive patients with diabetes mellitus.