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image of Hypertension-Mediated Organ Damages should be Divided into Acute and Chronic

Abstract

Introduction

High blood pressure (BP) damages various structures. The damaged structures are named hypertension-mediated organ damages (HMODs). Some of HMODs are acute (., intracranial haemorrhage), while the others are chronic (., left ventricular hypertrophy (LVH)). The aim of the paper was to investigate how HMODs compare to each other, and to answer the question of whether HMODs are divided into acute and chronic forms in the major medical publications – guidelines.

Methods

A search for ‘acute hypertension-mediated organ damage’ and ‘acute target organ damage’ was performed in the whole papers in SCOPUS. Moreover, the available guidelines on hypertension are analysed.

Results

Our results show that the mentioned chronic HMODs differ a lot, both in number and qualitatively, which HMODs are specified. The difference regarding the number of HMODs listed reflects partially the different approach; some guidelines state organ damage in general, and the other guidelines provide extensive lists.

Discussion

A substantial number of arterial hypertension (HTN) guidelines do not list both acute and chronic HMODs; several guidelines refer to acute HMODs, and some others to chronic HMODs. In a number of HTN guidelines, acute (., intracranial haemorrhage) and chronic HMODs (such as LVH) were mixed. In the vast majority of guidelines, the acute and chronic HMODs are not directly divided.

Conclusion

Consensus is clearly missing about the definition and classification of HMODs. Multiple reasons suggest that HMODs should be divided into acute and chronic subgroups. We presented some of the arguments and examples to start with.

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References

  1. Friedberg C.K. Diseases of the heart. 1949 Available from: https://ia800107.us.archive.org/6/items/in.ernet.dli.2015.547822/2015.547822.Diseases-of_text.pdf (accessed November 25, 2024).
    [Google Scholar]
  2. Mancia G. Kreutz R. Brunström M. 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension. J. Hypertens. 2023 41 12 1874 2071 10.1097/HJH.0000000000003480 37345492
    [Google Scholar]
  3. McEvoy J.W. McCarthy C.P. Bruno R.M. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension. Eur. Heart J. 2024 45 38 3912 4018 10.1093/eurheartj/ehae178 39210715
    [Google Scholar]
  4. Koracevic G. Stojanovic M. Kostic T. Lovic D. Tomasevic M. Jankovic-Tomasevic R. Unsolved Problem: (Isolated) Systolic Hypertension with Diastolic Blood Pressure below the Safety Margin. Med. Princ. Pract. 2020 29 4 301 309 10.1159/000508462 32380500
    [Google Scholar]
  5. Koracevic G. Mićić S. Stojanovic M. Significance of Beta-Blocker in Patients with Hypertensive Left Ventricular Hypertrophy and Myocardial Ischemia. Curr. Vasc. Pharmacol. 2023 21 2 81 90 10.2174/1570161121666230201141215 36722475
    [Google Scholar]
  6. Ettehad D. Emdin C.A. Kiran A. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet 2016 387 10022 957 967 10.1016/S0140‑6736(15)01225‑8 26724178
    [Google Scholar]
  7. Fuchs F.D. Whelton P.K. High Blood Pressure and Cardiovascular Disease. Hypertension 2020 75 2 285 292 10.1161/HYPERTENSIONAHA.119.14240 31865786
    [Google Scholar]
  8. Rossi G.P. Rossitto G. Maifredini C. Management of hypertensive emergencies: a practical approach. Blood Press. 2021 30 4 208 219 10.1080/08037051.2021.1917983 33966560
    [Google Scholar]
  9. Oh J.S. Lee C.H. Park J. Park H.K. Hwang J.K. Hypertension-Mediated Organ Damage and Long-term Cardiovascular Outcomes in Asian Hypertensive Patients without Prior Cardiovascular Disease. J. Korean Med. Sci. 2020 35 48 e400 10.3346/jkms.2020.35.e400 33316856
    [Google Scholar]
  10. Rossi G.P. Rossitto G. Maifredini C. Modern Management of Hypertensive Emergencies. High Blood Press. Cardiovasc. Prev. 2022 29 1 33 40 10.1007/s40292‑021‑00487‑1 34813055
    [Google Scholar]
  11. Kim H.L. Lee E.M. Ahn S.Y. The 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension. Clin. Hypertens. 2023 29 1 11 10.1186/s40885‑023‑00234‑9 36788612
    [Google Scholar]
  12. Tschanz C.M.P. Cushman W.C. Harrell C.T.E. Berlowitz D.R. Sall J.L. Synopsis of the 2020 U.S. Department of Veterans Affairs/U.S. Department of Defense Clinical Practice Guideline: The Diagnosis and Management of Hypertension in the Primary Care Setting. Ann. Intern. Med. 2020 173 11 904 913 10.7326/M20‑3798 32866417
    [Google Scholar]
  13. Van Minh H. Van Huy T. Long D.P.P. Tien H.A. Highlights of the 2022 Vietnamese Society of Hypertension guidelines for the diagnosis and treatment of arterial hypertension. J. Clin. Hypertens. (Greenwich) 2022 24 9 1121 1138 10.1111/jch.14580 36196473
    [Google Scholar]
  14. Interim guidelines for the clinical management of hypertension in ja-maica. 2020 Available from: https://www.moh.gov.jm/wp-content/uploads/2020/10/HYPERTENSIONGUIDELINES_Interim_final.pdf (accessed November 25, 2024).
  15. Williams B. Poulter N.R. Brown M.J. Guidelines for management of hypertension: Report of the fourth working party of the british hypertension society, 2004—BHS IV. J. Hum. Hypertens. 2004 18 3 139 185 10.1038/sj.jhh.1001683 14973512
    [Google Scholar]
  16. Rosas M Pastelín G Vargas-Alarcón G Guías clínicas para la detección, prevención, diagnóstico y tratamiento de hipertensión arterial sistémica en México 2008 [Clinical guidelines for detection, prevention, diagnosis and treatment of systemic arterial hypertension in Mexico (2008) Arch Cardiol Mex 2008; 78(Suppl 2): S2-5-57.Comité Institucional de Expertos en Hipertensión Arterial Sis-témica. 18928127
    [Google Scholar]
  17. Sanchez R.A. Ayala M. Baglivo H. Latin American guidelines on hypertension. J. Hypertens. 2009 27 5 905 922 10.1097/HJH.0b013e32832aa6d2 19349909
    [Google Scholar]
  18. van den Born B.J. Beutler J.J. Gaillard C.A. de Gooijer A. van den Meiracker A.H. Kroon A.A. Dutch guideline for the management of hypertensive crisis -- 2010 revision. Neth. J. Med. 2011 69 5 248 255 21646675
    [Google Scholar]
  19. Aronow W.S. Fleg J.L. Pepine C.J. ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly. Circulation 2011 123 21 2434 2506 10.1161/CIR.0b013e31821daaf6 21518977
    [Google Scholar]
  20. Mancia G. Fagard R. Narkiewicz K. 2013 ESH/ESC Guidelines for the management of arterial hypertension. Eur. Heart J. 2013 34 28 2159 2219 10.1093/eurheartj/eht151 23771844
    [Google Scholar]
  21. Wolf S.J. Lo B. Shih R.D. Smith M.D. Fesmire F.M. Clinical policy: critical issues in the evaluation and management of adult patients in the emergency department with asymptomatic elevated blood pressure. Ann. Emerg. Med. 2013 62 1 59 68 10.1016/j.annemergmed.2013.05.012 23842053
    [Google Scholar]
  22. EGYPTIAN HYPERTENSION GUIDELINES EGYPTIAN HYPERTENSION GUIDELINES. Egypt. Heart J. 2014 66 2 79 132 10.1016/j.ehj.2014.03.001
    [Google Scholar]
  23. James P.A. Oparil S. Carter B.L. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014 311 5 507 520 10.1001/jama.2013.284427 24352797
    [Google Scholar]
  24. Weber M.A. Schiffrin E.L. White W.B. Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension. J. Hypertens. 2014 32 1 3 15 10.1097/HJH.0000000000000065 24270181
    [Google Scholar]
  25. Seedat Y.K. Rayner B.L. Veriava Y. South African hypertension practice guideline 2014: review article. Cardiovasc. J. Afr. 2014 25 6 288 294 10.5830/CVJA‑2014‑062 25629715
    [Google Scholar]
  26. Tykarski A. Narkiewicz K. Gaciong Z. 2015 guidelines for the management of hypertension. Recommendations of the Polish Society of Hypertension — short version. Kardiol. Pol. 2015 73 8 676 700 10.5603/KP.2015.0157 26304155
    [Google Scholar]
  27. Gabb G.M. Mangoni A.A. Anderson C.S. Guideline for the diagnosis and management of hypertension in adults — 2016. Med. J. Aust. 2016 205 2 85 89 10.5694/mja16.00526 27456450
    [Google Scholar]
  28. Malachias M.V.B. Barbosa E.C.D. Martim J.F. Rosito G.B.A. Toledo J.Y. Passarelli O. 7th Brazilian Guideline of Arterial Hypertension: Chap-ter 14 - Hypertensive Crisis. Arq Bras Cardiol 2016 107 3 79 83 (Suppl. 3) 10.5935/abc.20160164 27819393
    [Google Scholar]
  29. Whelton P.K. Carey R.M. Aronow W.S. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. J. Am. Coll. Cardiol. 2018 71 19 e127 e248 10.1016/j.jacc.2017.11.006 29146535
    [Google Scholar]
  30. Tay J.C. Sule A.A. Chew E.K. Ministry of Health Clinical Practice Guidelines: Hypertension. Singapore Med. J. 2018 59 1 17 27 10.11622/smedj.2018007 29376186
    [Google Scholar]
  31. Kenya national guidelines for cardiovascular diseases management. 2018.Developed by the Division of Non-Communicable Diseases - Ministry of Health. Available from: www.health.go.ke (accessed No-vember 25, 2024). 2018
  32. SESLHD hypertension policy development working party manage-ment of hypertension in the SESLHD ward settings. South eastern Sydney local health district guideline. SESLHDGL/068. 2018 Available from: https://www.seslhd.health.nsw.gov.au/sites/default/files/documents/SESLHDGL068.pdf (accessed November 25, 2024).
  33. 2018 Chinese guidelines for prevention and treatment of hypertension-a report of the revision committee of chinese guidelines for prevention and treatment of hypertension. J. Geriatr. Cardiol. 2019 16 3 182 241 [Joint Committee for Guideline Revision. 10.11909/j.issn.1671‑5411.2019.03.014 31080465
    [Google Scholar]
  34. Academy of Medicine of Malaysia The clinical practise guidelines (CPGs); management of hypertension (5th edition) 2018. 2018 Available from: http://www.acadmed.org.my/index.cfm?menuid=67 (accessed November 25, 2024).
  35. Williams B. Mancia G. Spiering W. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur. Heart J. 2018 39 33 3021 3104 10.1093/eurheartj/ehy339 30165516
    [Google Scholar]
  36. Lee H.Y. Shin J. Kim G.H. 2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension. Clin. Hypertens. 2019 25 1 20 10.1186/s40885‑019‑0124‑x 31388453
    [Google Scholar]
  37. van den Born B.J.H. Lip G.Y.H. Brguljan-Hitij J. ESC Council on hypertension position document on the management of hypertensive emergencies. Eur. Heart J. Cardiovasc. Pharmacother. 2019 5 1 37 46 10.1093/ehjcvp/pvy032 30165588
    [Google Scholar]
  38. Umemura S. Arima H. Arima S. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019). Hypertens. Res. 2019 42 9 1235 1481 10.1038/s41440‑019‑0284‑9 31375757
    [Google Scholar]
  39. Hua Q. Fan L. Li J. 2019 Chinese guideline for the management of hypertension in the elderly. J. Geriatr. Cardiol. 2019 16 2 67 99 10.11909/j.issn.1671‑5411.2019.02.001 30923539
    [Google Scholar]
  40. Alcocer L Álvarez-López H Borrayo-Sánchez GB Cardona-Muñoz EG Chávez-Mendoza A Hypertension as a persistent public health problem. A position paper from Alliance for a Healthy Heart, Mex-ico. Annals of Clinical Hypertension 2019 3 1 009 30 10.29328/journal.ach.1001015
  41. Shah S.N. Munjal Y.P. Kamath S.A. Indian guidelines on hypertension-IV (2019). J. Hum. Hypertens. 2020 34 11 745 758 10.1038/s41371‑020‑0349‑x 32427886
    [Google Scholar]
  42. NICE guideline. Hypertension in adults: Diagnosis and management (NG136). 2024 Available from: www.nice.org.uk/guidance/ng136 (accessed November 25, 2024) .
  43. Vilela-Martin J.F. Yugar-Toledo J.C. Rodrigues M.C. Luso-brazilian position statement on hypertensive emergencies. Arq. Bras. Cardiol. 2020 Apr.114 4 736 751 10.36660/abc.20190731 32491016
    [Google Scholar]
  44. Rabi D.M. McBrien K.A. Sapir-Pichhadze R. Hypertension canada’s 2020 comprehensive guidelines for the prevention, diagnosis, risk assessment, and treatment of hypertension in adults and children. Can. J. Cardiol. 2020 36 5 596 624 10.1016/j.cjca.2020.02.086 32389335
    [Google Scholar]
  45. Hypertension – diagnosis and management (2020). 2020.BCGuide-lines.ca. 2020 Available from:https://www2.gov.bc.ca/gov/content/health/practitioner-professional-resources/bc-guidelines/hypertension (accessed November 25, 2024).
  46. Wyss F. Coca A. Lopez-Jaramillo P. Position statement of the interamerican society of cardiology (IASC) on the current guidelines for the prevention, diagnosis and treatment of arterial hypertension 2017–2020. Int. J. Cardiol. Hypertens. 2020 6 100041 [Task Force for the management of Arterial Hypertension of the Interamerican Society of Cardiology (IASC); Reviewers from European Society of Hypertension (ESH) [, Latin-American Society of Hypertension (LASH) [, Spanish Society of Cardiology [SSC] 10.1016/j.ijchy.2020.100041 33447767
    [Google Scholar]
  47. Unger T. Borghi C. Charchar F. 2020 International society of hypertension global hypertension practice guidelines. Hypertension 2020 75 6 1334 1357 10.1161/HYPERTENSIONAHA.120.15026 32370572
    [Google Scholar]
  48. Vasan R.S. Song R.J. Xanthakis V. Hypertension-mediated organ damage: Prevalence, correlates, and prognosis in the community. Hypertension 2022 79 3 505 515 10.1161/HYPERTENSIONAHA.121.18502 35138872
    [Google Scholar]
  49. Nath B. Dorairaj P. Nair T. Aurora A. Sengupta S. Sharma U.P. Hypertension-mediated organ damage care in india go-real (guidelines to real world) application: Expert opinion. J. Assoc. Physicians India 2025 73 3 e7 e21 10.59556/japi.73.0877 40087938
    [Google Scholar]
  50. Miceli F. Presta V. Citoni B. Conventional and new electrocardiographic criteria for hypertension‐mediated cardiac organ damage: A narrative review. J. Clin. Hypertens. 2019 21 12 1863 1871 10.1111/jch.13726 31693279
    [Google Scholar]
  51. Rizzoni D. Agabiti-Rosei C. De Ciuceis C. Boari G.E.M. Subclinical hypertension-mediated organ damage (HMOD) in hypertension: Atherosclerotic cardiovascular disease (ASCVD) and calcium score. High Blood Press. Cardiovasc. Prev. 2022 30 1 17 27 10.1007/s40292‑022‑00551‑4 36376777
    [Google Scholar]
  52. Piskorz D. Hypertensive mediated organ damage and hypertension management. how to assess beneficial effects of antihypertensive treatments? High Blood Press. Cardiovasc. Prev. 2020 27 1 9 17 10.1007/s40292‑020‑00361‑6 31975151
    [Google Scholar]
  53. Koracevic G. Stojanovic M. Lovic D. Radovanovic R.V. Koracevic M. Rationale for the concept of impending hypertension-mediated organ damage. Curr. Vasc. Pharmacol. 2022 20 2 127 133 10.2174/1570161120666220124105846 35068394
    [Google Scholar]
  54. Ingelfinger J. Hypertension in children with kidney transplants. In: Gruskin A, Meads N, Eds. Pediatric nephrology. Gruskin A. Meads N. Boston Nijhoff 1981 376 382 10.1007/978‑94‑009‑8319‑9_50
    [Google Scholar]
  55. Palatini P. Exaggerated blood pressure response to exercise: pathophysiologic mechanisms and clinical relevance. J. Sports Med. Phys. Fitness 1998 38 1 1 9 9638025
    [Google Scholar]
  56. Kim Y. Cho J.S. Cho W. Retinopathy and left ventricular hypertrophy in patients with chronic kidney disease: Interrelationship and impact on clinical outcomes. Int. J. Cardiol. 2017 249 372 376 10.1016/j.ijcard.2017.06.123 29121742
    [Google Scholar]
  57. Koracevic G. Stojanovic M. Lovic D. Djordjevic D. Impending hypertensive emergency is frequently considered in guidelines, but neither defined nor explained. Blood Press. 2020 29 5 336 337 10.1080/08037051.2020.1769467 32441140
    [Google Scholar]
  58. Koracevic G. Stojanovic M. Lovic D. Blood pressure cut-offs to diagnose impending hypertensive emergency depend on previous hypertension-mediated organ damage and comorbid conditions. Natl. Med. J. India 2024 36 4 257 262 10.25259/NMJI_160_21 38692626
    [Google Scholar]
  59. Koracevic G. Stojanovic M. Zdravkovic M. Lovic D. Simic D. Mladenovic K. Proposal of a Modified Classification of Hypertensive Crises: Urgency, Impending Emergency, and Emergency. Curr. Vasc. Pharmacol. 2024 22 3 180 186 10.2174/0115701611270174231204110557 39188222
    [Google Scholar]
  60. Thygesen K. Alpert J.S. Jaffe A.S. Fourth Universal Definition of Myocardial Infarction (2018). Circulation 2018 138 20 e618 e651 10.1161/CIR.0000000000000617 30571511
    [Google Scholar]
  61. Zdravkovic M. Klasnja S. Popovic M. Cardiac magnetic resonance in hypertensive heart disease: Time for a new chapter. Diagnostics 2023 13 1 137 10.3390/diagnostics13010137
    [Google Scholar]
  62. Koracevic G. Perisic Z. Stanojkovic M. A discrepancy: Calcium channel blockers are effective for the treatment of hypertensive left ventricular hypertrophy but not as effective for prevention of heart failure. Med. Princ. Pract. 2022 31 5 454 462 10.1159/000526792 36044874
    [Google Scholar]
  63. Đorđević D.B. Koračević G.P. Đorđević A.D. Lović D.B. Hypertension and left ventricular hypertrophy. J. Hypertens. 2024 42 9 1505 1515 10.1097/HJH.0000000000003774 38747417
    [Google Scholar]
  64. Koraćević G. Mićić S. Stojanović M. Beta-blockers in hypertensive left ventricular hypertrophy and atrial fibrillation prevention. Curr. Vasc. Pharmacol. 2024 22 1 19 27 10.2174/0115701611264647231110101700 38031765
    [Google Scholar]
  65. Gallo G. Savoia C. Hypertension and heart failure: From pathophysiology to treatment. Int. J. Mol. Sci. 2024 25 12 6661 10.3390/ijms25126661 38928371
    [Google Scholar]
  66. Viau D.M. Sala-Mercado J.A. Spranger M.D. O’Leary D.S. Levy P.D. The pathophysiology of hypertensive acute heart failure. Heart 2015 101 23 1861 1867 10.1136/heartjnl‑2015‑307461 26123135
    [Google Scholar]
  67. Shiraishi Y. Kohsaka S. Abe T. Impact of triggering events on outcomes of acute heart failure. Am. J. Med. 2018 131 2 156 164.e2 [Tokyo CCU Network Scientific Committee. 10.1016/j.amjmed.2017.09.008 28941748
    [Google Scholar]
  68. Shin J.H. Kim B.S. Lyu M. Clinical characteristics and predictors of all-cause mortality in patients with hypertensive urgency at an emergency department. J. Clin. Med. 2021 10 19 4314 10.3390/jcm10194314 34640330
    [Google Scholar]
  69. Kim W. Kim B.S. Kim H.J. Lee J.H. Shin J. Shin J.H. Clinical implications of cardiac troponin-I in patients with hypertensive crisis visiting the emergency department. Ann. Med. 2022 54 1 507 515 10.1080/07853890.2022.2034934 35112971
    [Google Scholar]
  70. Kim B.S. Lee Y. Lim Y.H. Shin J. Shin J.H. Association between B-type natriuretic peptide and long-term mortality in patients with acute severe hypertension visiting the emergency department. Sci. Rep. 2022 12 1 21001 10.1038/s41598‑022‑25705‑1 36470945
    [Google Scholar]
  71. Kim B.S. Shin J.H. Association between D-dimer and long-term mortality in patients with acute severe hypertension visiting the emergency department. Clin. Hypertens. 2023 29 1 16 10.1186/s40885‑023‑00244‑7 37316924
    [Google Scholar]
  72. Yu M.Y. Park J.K. Kim B.S. Kim H.J. Shin J. Shin J.H. Association of microscopic hematuria with long-term mortality in patients with hypertensive crisis. J. Nephrol. 2022 36 1 147 155 10.1007/s40620‑022‑01421‑x 36001296
    [Google Scholar]
  73. Kim W.D. Kim B.S. Shin J.H. Association of anaemia with long-term mortality among patients with hypertensive crisis in the emergency department. Ann. Med. 2022 54 1 2740 2747 10.1080/07853890.2022.2128209 36205691
    [Google Scholar]
  74. Kim H.J. Kim B.S. Lee J.H. Shin J.H. Impact of underweight on 3-year all-cause mortality in patients with acute severe hypertension: A retrospective cohort study. Sci. Rep. 2022 12 1 4798 10.1038/s41598‑022‑08892‑9 35314748
    [Google Scholar]
  75. Talle M.A. Doubell A.F. Robbertse P.P.S. Lahri S. Herbst P.G. Cardiac morphology, function, and left ventricular geometric pattern in patients with hypertensive crisis: A cardiovascular magnetic resonance-based study. J. Cardiovasc. Dev. Dis. 2023 10 9 367 10.3390/jcdd10090367 37754796
    [Google Scholar]
  76. Manolis A.J. Kallistratos M.S. Koutsaki M. The diagnostic approach and management of hypertension in the emergency department. Eur. J. Intern. Med. 2024 121 17 24 10.1016/j.ejim.2023.11.028 38087668
    [Google Scholar]
  77. Benenson I. Waldron F.A. Holly C. A systematic review and meta-analysis of the clinical and Epidemiological characteristics of patients with hypertensive emergencies: implication for risk stratification. High Blood Press. Cardiovasc. Prev. 2023 30 4 319 331 10.1007/s40292‑023‑00586‑1 37284909
    [Google Scholar]
  78. Kotruchin P. Tangpaisarn T. Mitsungnern T. Hypertensive emergencies in asia: A brief review. J. Clin. Hypertens. 2022 24 9 1226 1235 10.1111/jch.14547 36196470
    [Google Scholar]
  79. Cheung C.Y. Biousse V. Keane P.A. Schiffrin E.L. Wong T.Y. Hypertensive eye disease. Nat. Rev. Dis. Primers 2022 8 1 14 10.1038/s41572‑022‑00342‑0 35273180
    [Google Scholar]
  80. Ker J.A. Outhoff K. Hypertension – back to basics. S. Afr. Pharm. J. 2023 90 5 29 34
    [Google Scholar]
  81. Lembo M. Pacella D. Manzi M.V. Hypertension-mediated organ damage involving multiple sites is an independent risk factor for cardiovascular events. Eur. Heart J. Open 2023 3 5 oead102 10.1093/ehjopen/oead102 37881599
    [Google Scholar]
  82. Shirafkan A. Motahari M. Mojerlou M. Rezghi Z. Behnampour N. Gholamrezanezhad A. Association between left ventricular hypertrophy with retinopathy and renal dysfunction in patients with essential hypertension. Singapore Med. J. 2009 50 12 1177 1183 20087555
    [Google Scholar]
  83. Shigematsu Y. Hamada M. Okayama H. Left ventricular hypertrophy precedes other target-organ damage in primary aldosteronism. Hypertension 1997 29 3 723 727 10.1161/01.HYP.29.3.723 9052887
    [Google Scholar]
  84. Nardi E. Mulè G. Giammanco A. Left ventricular hypertrophy in chronic kidney disease: A diagnostic criteria comparison. Nutr. Metab. Cardiovasc. Dis. 2021 31 1 137 144 10.1016/j.numecd.2020.08.028 33092976
    [Google Scholar]
  85. Fragoulis C. Lazarou E. Tsioufis K. Hypertensive emergencies: Still an emergency? J Hypertens Res 2021 7 4 119 123
    [Google Scholar]
  86. Balahura A.M. Moroi Ș.I. Scafa-Udrişte A. The management of hypertensive emergencies—is there a “magical” prescription for all? J. Clin. Med. 2022 11 11 3138 10.3390/jcm11113138 35683521
    [Google Scholar]
  87. Charchar F.J. Prestes P.R. Mills C. Lifestyle management of hypertension: International society of hypertension position paper endorsed by the world hypertension league and european society of hypertension. J. Hypertens. 2024 42 1 23 49 10.1097/HJH.0000000000003563 37712135
    [Google Scholar]
  88. Cai M. Jiang F. Lin L. Poor sleep quality is a risk factor for adverse clinical outcomes in patients with acute aortic dissection: A prospective cohort study. J. Sleep Res. 2024 34 4 e14411 10.1111/jsr.14411 39568144
    [Google Scholar]
  89. Isselbacher E.M. Preventza O. Hamilton Black J. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease. J. Thorac. Cardiovasc. Surg. 2023 166 5 e182 e331 [Writing Committee Members; Peer Review Committee Members; AHA/ACC Joint Committee Members. 10.1016/j.jtcvs.2023.04.023 37389507
    [Google Scholar]
  90. Genç Yavuz B. Söğüt O. Çolak S. Koldaş M. Yücetaş E. Bari O. Low serum corin levels predict end-organ damage in patients with hypertensive crisis. Anatol. J. Cardiol. 2021 25 8 536 543 10.5152/AnatolJCardiol.2021.06698 34369881
    [Google Scholar]
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Hypertension-Mediated Organ Damages should be Divided into Acute and Chronic
Bentham Science Publishers ; https://doi.org/10.2174/0115734021387631251016141754
/content/journals/chyr/10.2174/0115734021387631251016141754
/content/journals/chyr/10.2174/0115734021387631251016141754
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  • Article Type:     Review Article
Keywords: guidelines ; Arterial hypertension ; acute target organ damage ; intracranial haemorrhage ; left ventricular hypertrophy ; hypertension-mediated organ damage

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