Full text loading...
- ISSN: 1871-5257
- E-ISSN: 1875-6182
-
The Effects of Direct Renin Inhibitor, Aliskiren, on Arterial Hypertension, Chronic Kidney Disease and Cardiovascular Disease: Optimal Pharmacotherapy
- Source: Cardiovascular & Hematological Agents in Medicinal Chemistry, Volume 11, Issue 1, Mar 2013, p. 77 - 82
-
- 01 Mar 2013
Abstract
The renin-angiotensin-aldosterone system (RAAS) plays pivotal roles in the pathogenesis of progression of arterial hypertension, chronic kidney disease (CKD) and cardiovascular disease (CVD). Previous studies suggested that a direct renin inhibitor, aliskiren, may be effective for blood pressure lowering, renoprotection and cardiovascular protection. This review focuses on the effects of aliskiren for arterial hypertension, CKD and CVD.
© Bentham Science Publishers