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- ISSN: 1871-5257
- E-ISSN: 1875-6182
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Advances in Sickle Cell Disease Treatment: from Drug Discovery Until the Patient Monitoring
- Source: Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents), Volume 9, Issue 2, Apr 2011, p. 113 - 127
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- 01 Apr 2011
Abstract
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in last years few therapeutical sources are currently available. Nowadays the treatment is performed mainly with drugs such as hydroxyurea or other fetal hemoglobin inducers and chelating agents. This review summarizes current knowledge about the treatment and the advancements in drug design in order to discover more effective and safe drugs. Patient monitoring methods in SCD are also discussed.
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