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2000
Volume 3, Issue 3
  • ISSN: 2666-8629
  • E-ISSN: 2666-8637

Abstract

Diabetes is an enormously understood disorder, having a paramount disease burden globally. Although treatments are available for the management of the disease, there are associated side effects. A deep-rooted need is to have a comprehensive treatment without any ramifications. Ethnomedicine has been practised in various regions and cultures for ages. However, a lack of significant scientific data has been a drawback for such treatment and its formulations. There is increasing empirical evidence for various phytoconstituents showing promising results for addressing the pathophysiology of diabetes. A plethora of phytoconstituents have been reported, and their mechanisms have been understood in detail. In this scenario, bioactive isolates obtained from marine algae offer numerous opportunities for managing the intricate blood-glucose dynamics associated with diabetes. Marine algal phytoconstituents inhibited several diabetes enzymes and improved serum parameters, which have also been shown to have antioxidant, anti-inflammatory, anti-obesity, and other therapeutic actions through and research. Hence, this article reviews the major marine phytoconstituents from macroalgae and their molecular mechanisms for managing diabetes. The results of this review indicate that marine bioactive components have demonstrated high potential to mitigate diabetes, but there have not been many clinical trials done in this area. A principal strategy for the success of any drug discovered belongs to commercialization, including clinical trials and production feasibility. The article also elaborates on the current challenges associated with the supply and consumption of commercial phytoconstituents.

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/content/journals/cff/10.2174/0126668629339331241121111615
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Marine Algae as a Potential Source of Bioactive Compounds for the Management of Diabetes
Curr Func Foods 3, E26668629339331 (2025); https://doi.org/10.2174/0126668629339331241121111615
/content/journals/cff/10.2174/0126668629339331241121111615
/content/journals/cff/10.2174/0126668629339331241121111615
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  • Article Type:     Review Article
Keyword(s): antioxidants; Diabetes; drug targets; enzymes; marine algae; mechanisms; phytoconstituents

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