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- Volume 17, Issue 1, 2022
Current Drug Therapy - Volume 17, Issue 1, 2022
Volume 17, Issue 1, 2022
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Emerging Trends and their Impacts on Peptic Ulcer Diseases: Treatments and Techniques
Authors: Pranjal K. Singh and T.S. EaswariBackground: Peptic ulcer disease (PUD) is prevalent in almost all parts of the world. PUD complications are a major source of health care expenses; however, they are preventable. The major factors responsible for the incidence of PUD and its complication have changed over the past few decades after the identification of non-steroidal inflammatory drugs (NSAIDs) and Helicobacter pylori bacterial infection along with a ma Read More
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In vivo and In vitro Anti-hydatidosis Effect of Garlic: A Systematic Review
Background: Hydatidosis is a parasitic disease caused by the larval stage of Echinococcus granulosus sensu lato. The aim of the current systematic review study was to clarify the effect of garlic on hydatid cyst in vivo and in vitro. Methods: We performed our analyses up to Feb 20, 2021, in accordance with the PRISMA guideline. We systematically searched five English databases (Science Direct, PubMed, Scopus, Ovid and C Read More
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Optimization and Validation of Polyherbal Formulation by Applying Boxbehnken Design for the Treatment of Inflammatory Bowel Disease in Experimental Animals
Authors: Tejal Gandhi, Bhagyabhumi Patel, Divya Patel, Saloni Dalwadi and Vaishali ThakkarBackground: The use of herbal medicine in inflammatory bowel disease (IBD) has increased significantly. Allopathic treatment of IBD leads to several side effects; therefore, the use of the herbal formulation is promising. Aegle Marmelos, Bombax malabericum, and Hollarrhena antidysentrica plants have been used to treat IBD. Objective: This study aimed to evaluate a designed polyherbal formulation in experim Read More
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The Spectrum of Cefditoren for Lower Respiratory Tract Infections (LRTIs) in Surabaya
Background: Empirical antibiotics among outpatients with Lower Respiratory Tract Infections (LRTIs) are scarcely allocated in Indonesia. The study aims to evaluate the pathogens causing LRTIs, drug sensitivity test and the minimum inhibitory concentrations of 90% (MIC90) of Cefditoren, Azithromycin, Amoxicillin-Clavulanic Acid, and Cefixime. Methods: The study was performed in adult outpatients with LRTI that can be ex Read More
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Investigating the Effects of Aqueous and Alcoholic Extracts of Allium hirtifolium and Allium jesdianum on Keratinase Activity of Trichophyton Mentagrophytes
Authors: Maryam Sarlak, Zahra Nasiri, Mahboobeh Madani, Kahin Shahanipour, Elena Tognoni and Pegah ShakibBackground: Trichophyton spp., as pathogenic species to humans and animals, cause different forms of dermatophytosis through the production of particular enzymes, playing an essential role in tissue invasion. Among these, herein, keratinase was investigated, for the specific case of Trichophyton mentagrophytes, as a target of the effects of Allium hirtifolium and Allium jesdianum extracts, thus pharmacological poten Read More
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Activity of Fosfomycin against the Spectrum of Uropathogens Causing Cystitis
Background: Urinary tract infections (UTIs) are the most frequent bacterial infections commonly seen in females. A high degree of antimicrobial resistance in uropathogens has challenged the use of therapeutic agents. Fosfomycin, which is an old antibiotic with distinctive characteristics, seems to be a promising novel therapeutic agent with a good bactericidal activity towards multi-drug resistant (MDR) uropathogens. Obj Read More
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Effect of Silver Nanoparticles (AgNPs) on Candida albicans, Candida dubliniensis and Candida guilliermondii
Authors: Mahnaz Masoumizadeh, Mahboobeh Madani, Soheil Fatahian and Pegah ShakibBackground: Candida species are the most important fungal pathogens and are sometimes considered the fourth most common cause of infection in hospitals. Today, research needs to be conducted on the antifungal effect of silver nanoparticles (AgNPs) due to toxicity, side effects, and drug interactions of antifungal chemical drugs. Objective: Therefore, this study was conducted to evaluate the antifungal activity of AgNPs on Read More
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Poloxamer based Urapidil Loaded Chitosan Microparticle in Approach to Improve the Mechanical Strength by Tensile Strength and Entrapment Determination
Authors: Harekrishna Roy, Bhabani S. Nayak and Sisir NandiBackground: The literature review has highlighted the issues related to the poor mechanical strength of chitosan-based microparticles. In an attempt to resolve the drawbacks, the microparticles were prepared with a suitable combination of poloxamer-188 (pluronic) and chitosan-based hydrogels. Objective: The current study dealt with urapidil-loaded chitosan microparticles incorporating chitosanbased hydrogels and sm Read More
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Volumes & issues
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Volume 20 (2025)
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Volume 19 (2024)
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Volume 18 (2023)
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Volume 17 (2022)
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Volume 16 (2021)
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Volume 15 (2020)
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Volume 14 (2019)
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Volume 13 (2018)
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Volume 12 (2017)
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Volume 11 (2016)
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Volume 10 (2015)
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Volume 9 (2014)
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Volume 8 (2013)
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Volume 7 (2012)
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Volume 6 (2011)
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Volume 5 (2010)
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Volume 4 (2009)
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Volume 3 (2008)
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Volume 2 (2007)
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Volume 1 (2006)
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