Current Chinese Science - Volume 2, Issue 2, 2022
Volume 2, Issue 2, 2022
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Efficient Fluorescent Detection of Mercuric Ions Based on 2-Thienyl benzimidazole/Cucurbit[7]uril Complexes
Authors: Marieh B. Al-Handawi, John P. Graham, Hany A. Eldeab and Na'il SalehAims and objective: 2-Thienylbenzimidazole (TBI)/cucurbit[7]uril (CB7) host/guest complex was used to significantly improve the detection of Hg2+ in water samples. Methods: The unique mechanism of the sensing process is based on the binding of CB7 host to TBI guest. The host-guest complexation was confirmed by UV-visible absorption, time-resolved fluorescence, and proton NMR spectroscopy. The complexations of Read More
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Computational Studies of Budesonide vs. Vilanterol: Asthma Drugs Against SARS-CoV-2 Mpro
Authors: Afzal Hussain and Ashfaq HussainThe global spread of SARS-CoV-2 and the mortality it has caused have prompted research organizations to develop novel medications to combat COVID-19 infection. The main protease (Mpro) of SARS-CoV-2 is crucial for the virus's replication and propagation in host cells. Therefore, it is a promising therapeutic target. There are officially no certified specific drugs or available interventions for COVID-19 infection. Repurposin Read More
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Electronic and Magnetic Properties of Eutectoid Growth Mn-rich Ge1-xMnx Dilute Magnetic Semiconductors
Authors: Xiuxiu Zhang, Hui Su and Qinghua LiuBackground: Dilute magnetic semiconductors (DMSs) have attracted great attention in recent years due to their potential applications in spintronic devices. Objective: This study aimed to investigate the magnetic and electronic properties of Mn-rich Ge semiconductors. Methods: The magnetic and electronic properties of eutectoid growth Mn-rich Ge1-xMnx dilute magnetic semiconductors (DMSs) with a high Mn dopant close to Read More
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Feedstock: A Solution to Energy and Environment Sustainability
Authors: Kinjal J. Shah, Satyendra Tripathi, Touseef Hussain and Zhaoyang YouBackground: Scarcity of resources, energy crisis, environmental pollution and climate change are the central challenges that people will have to face in the years to come. Nowadays, agricultural, food and industrial wastes are generated in large quantities, which poses a serious problem in their management and disposal. Objective: Feedstocks play a vital role in solving energy and environmental problems. All renewable, bio Read More
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Supervised Machine Learning Models and Protein-Protein Interaction Network Analysis of Gene Expression Profiles Induced by Omega-3 Polyunsaturated Fatty Acids
Background: Omega-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, have beneficial effects on human health, but their effect on gene expression in elderly individuals (age ≥ 65) is largely unknown. In order to examine this, the gene expression profiles were analyzed in the healthy subjects (n = 96) at baseline and after 26 weeks of supplementation with EPA+DHA to d Read More
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(+)-Nootkatone: Progresses in Synthesis, Structural Modifications, Pharmacology and Ecology Uses
Authors: Yu-Bin Wang, Jian-Long Li, Fang-Fang Xu, Xiao-Dong Han, Yun-Shan Wu and Bo Liu(+)-Nootkatone is a type of eremophilane naturally derived sesquiterpenoids with a grapefruit smell from plants, widely used in the food and cosmetics industries. Many investigations elucidated that (+)-nootkatone presents extensive pharmacological activity, such as antiproliferation in cancer cells, anti-inflammatory, antioxidant nitration stress, etc. In addition, (+)- nootkatone has been registered by the Environmental Read More
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Protective Role of Eupafolin against Tumor, Inflammation, Melanogenesis, Viral Disease and Renal Injury: Pharmacological and Analytical Aspects through Scientific Data Analysis
More LessBackground: Plant derived natural products have always been used in medicine for the treatment of human disorders due to their pharmacological activities and safety profile. Plant derived natural products have been used in food, nutraceuticals, and medicine for better growth and development. Phytoconstituents are pure chemicals derived from various plant materials, and some of the best examples are tannins, a Read More
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Efficient Control of the Formation of Pillar[5]arene-based Supramolecular Polymers
Authors: Luzhi Liu, Qin He, Qingqing Zhou, Xue Qin, Wenxue Zhang, Yan Huang and Wengui DuanBackground: The design and preparation of functional pillar[n]arene-based supramolecular polymers have attracted extensive attention due to their wide range of applications. Objective and Methods: Based on the synergistic effects of non-covalent interactions, including hydrogen bonds and host-guest interaction, an amphiphilic pillar[5]arene 1 with two terminated acid chains was designed, and its self-assembly propertie Read More
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Regenerative Medicine for Neonatal Wound Healing
Authors: Genieve E. C. Yeo and Jia X. LawNeonates, especially premature newborns, have delicate skin that is susceptible to injury. Furthermore, they may acquire congenital skin diseases such as epidermolysis bullosa and aplasia cutis congenita that need prompt and effective treatment to reduce morbidity and mortality. Conventional management involves the covering of wound with a dressing, e.g., hydrogel, hydrocolloid and hydrofiber, which can maint Read More
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