Current Chromatography - Volume 5, Issue 1, 2018

Background: The use of diamond as a chromatographic stationary phase has been studied for more than 45 years now. Detonation nanodiamonds (DND) have been regularly used to increase the low specific surface area of these non-porous stationary phases. Recently, core-shell particles with multiple layers of polyallylamine (PAAm) and DND have been reported for liquid chromatographic separations and solid phase extraction Read More

Background: In everyday practice, it is necessary to carry out the most number of analyses in the shortest possible time. Therefore, chromatographic systems must usually work above the optimum linear velocity, in order to obtain efficient separations and fast analysis. Objective: This review illustrates the main advantages of the new generation of core-shell particles with respect to the modern totally porous sub 2 Read More

Introduction: The development of new stationary phases is a continuing aspect in the improvement of separations in HPLC. Relatively few new separation materials get beyond the exploratory stage as reported in the research literature and become commercially viable products with wide-spread use. One such class of stationary phases, those based on silica hydride and chemically modified silica hydride, has become more Read More

Background: The retention mechanisms of hydrophilic interaction liquid chromatography (HILIC) have been reported as inconclusive and of mixed mode, and have not been explained quantitatively. Packing materials used in HILIC are bare silica gel, polar bonded-silica gels, and ion-exchangers. The chromatography is performed in aqueous solution. Under such condition, the stability of these packing materials is not guaranteed Read More

Background: In the criminal expertise exams routine, documents with aged appearance are quite common. A frequent type of fraud is the use of tea or coffee to produce yellowish color on paper, making the paper look older. One way to identify this kind of fraud is caffeine detection on paper. Objectives: This paper introduces a case study from Brasilian Federal Police that involved office receipts with aged appearance, in which Read More

Background: Food comes into contact with many chemicals during cultivation and storage, such as alkylphenols and phthalates. These compounds can bring harm to human health and therefore its residual quantification in food is needed. Methods: In this study, a new method for determination of 4-octylphenol, 4-tert-octylphenol, 4-nonylphenol, 4-tert-butylphenol, dibutylphthalate and benzylbutylphthalate was developed using s Read More

Background: Usually, diphteria toxin concentration and purification are performed after detoxification due to its high danger. In this work, an alternative diphteria toxoid (DTx) concentration and purification method by affinity chromatography is proposed. Methods: Screening of 19 triazinic dyes for selecting the best ligand for DTx concentration and purification by affinity chromatography was performed. Results: Cibacron Bl Read More