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Abstract

The search for novel neuroprotective and antioxidant agents is crucial in combating neurodegenerative diseases and oxidative stress-related disorders. This study explores the neuroprotective and antioxidant properties of (commonly known as Spirulina), a renowned for its rich nutritional profile and potential health benefits. has gained attention for its high content of bioactive compounds, including phycocyanin, carotenoids, and essential fatty acids, 60% protein, 8% fats, 15-25% Carbohydrates, minerals, vitamins, and pigments which are thought to contribute to its therapeutic and nutritional effects. In this research, was evaluated for its neuroprotective and antioxidant capabilities through a series of and experiments. The study utilized cell-based assays to assess the ability of extracts to protect neuronal cells from oxidative damage induced by various stressors, including hydrogen peroxide and glutamate. Additionally, the study employed animal models to further investigate the effects of on cognitive function and oxidative stress . The findings revealed that extracts exhibited significant antioxidant activity, as demonstrated by their ability to neutralize free radicals and reduce oxidative stress markers in neuronal cells. assays showed that enhanced cellular viability and reduced markers of oxidative damage, such as malondialdehyde (MDA) and reactive oxygen species (ROS). These results suggest that possesses potent antioxidant properties that can mitigate oxidative stress and protect neuronal cells. studies using rodent models further confirmed the neuroprotective effects of . Animals supplemented with showed improved cognitive performance in behavioral tests, including memory and learning tasks. Additionally, histological analysis revealed a reduction in neuroinflammation and neuronal damage in the brains of -treated animals. Biochemical assays supported these findings, indicating a decrease in oxidative stress markers and an increase in endogenous antioxidant enzyme activities.

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2025-10-06
2026-02-28

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/content/journals/cas/10.2174/0118746098365217250828003543
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Neuroprotective and Antioxidant Study of Cyanobacteria Arthrospira
Bentham Science Publishers ; https://doi.org/10.2174/0118746098365217250828003543
/content/journals/cas/10.2174/0118746098365217250828003543
/content/journals/cas/10.2174/0118746098365217250828003543
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  • Article Type:     Review Article
Keywords: spirulina ; Neuroprotection ; antioxidant activity ; phycocyanin ; oxidative stress ; cyanobacteria arthrospira

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