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Volume 23, Issue 3
  • ISSN: 2211-3525
  • E-ISSN: 2211-3533

Abstract

Introduction

Fungal infections are growing more rapidly and becoming a public health concern worldwide. The use of herbal medicines is now increasing due to their many functional properties with fewer side effects. , an important medicinal plant, exhibits many therapeutic properties.

Methods

In this article, the active phytoconstituents of were explored for their multitargeting activity as anti-inflammatory and antifungal by computational analysis.

Results

A total of nine phytoconstituents including 3,6-di-O-galloyl-D-glucose, Mucic acid-1,4-lactone-2-O-gallate, Mucic acid-1,4-lactone-5-O-gallate, Mucic acid-1,4-lactone-3-O-gallate, Mucic acid-1,4-lactone-3,5-di-O-gallate, 2,6-dimethoxy-4-(2-hydroxyethyl)phenol-1-O-beta-D-glucopyranoside, Apigenin-7-O-(6'-butyryl-beta-glucopyranoside), S-eriodictoyl-7-O-(6'-O-trans-p-coumaryl)-beta-D-glucopyranoside, and 1,2,3,4,6-penta-O-galloyl glucose showed better results as compared to standard drugs taken in the study.

Conclusion

Further, these constituents indicated good ADME properties during the SwissADME online analysis.

© 2025 Bentham Science Publishers
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2024-08-08
2025-03-25

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Successful Identification of Key Phytoconstituents of Emblica officinalis as Potential Multitargeting Anti-Inflammatory and Antifungal Agents
Anti Infect. Agents 23, E22113525331096 (2025); https://doi.org/10.2174/0122113525331096240801103353
/content/journals/aia/10.2174/0122113525331096240801103353
/content/journals/aia/10.2174/0122113525331096240801103353
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  • Article Type:     Research Article
Keyword(s): ADME properties; anti-fungal; anti-inflammatory; Emblica officinalis; Herbal; multitargeting

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