Quinones: A Privileged Moiety for Drug Discovery
Abstract
A multidisciplinary exploration of quinones as a vital structural class in medicinal chemistry Drawing from both natural and synthetic sources, the book explores the structural diversity, reactivity, and therapeutic potential of quinone compounds, positioning them as privileged moieties in the development of pharmacologically active agents.
The text covers essential themes such as synthesis strategies, identification techniques, biochemical relevance, and pharmacodynamics of quinones and their derivatives. It delves into their traditional use in medicine, contemporary roles in treating diseases like cancer and infections, and their capacity to interact with multiple biological targets. Specific chapters discuss glyco hybrids, ROS generation, enzymatic pathways, and toxicity profiles, offering a comprehensive overview of their medicinal versatility.
Key features:
Explores synthesis and structural modification techniques
Analyzes biochemical and pharmacodynamic mechanisms
Reviews traditional and modern therapeutic uses
Examines toxicity concerns and safety profiles
Highlights marketed drugs and emerging candidates
Presents recent studies and future trends.
