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Gut Microbiota in Type 2 Diabetes

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Type 2 Diabetes mellitus (T2DM), a chronic metabolic disorder characterized by insulin resistance and relative insulin deficiency, has emerged as a significant public health challenge globally due to its rapidly increasing prevalence. Growing evidence, as demonstrated by various studies, show that there is a significant association between the development of T2DM and disturbance in the composition profile of gut microbiota, which has generated interest in establishing the roles played by various metabolites derived from the gut microbiota in the development of T2DM. New approaches to treat T2DM by regulating the gut microbiota using probiotics, prebiotics, synbiotics, and fecal microbiota transplantation have generated significant interest.

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