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2000

Recent Advances in the Synthesis of C-Glycosides Using Glycals and their Derivatives

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A glycoside is recognized as a C-glycoside when the anomeric carbon of a sugar moiety is linked to an aglycone or another carbohydrate, creating a new C-C bond. Recently, C-glycosides have been recognized as a privileged class of carbohydrates owing to their extensive application in medicinal chemistry and drug discovery. These glycosides have played a vital role in designing various drug candidates owing to their stability towards acidic or enzymatic degradation. This chapter deals with the recent advances in the synthesis of privileged C-glycosides, including 2-deoxy-C-glycosides, using glycals and their derivatives.

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