The Therapeutic Potential of Nanoparticles in Healthcare

- Authors: Twinkle Rout1, Soumyashree Rout2, Bhangyashree Nanda3, Arun Kumar Pradhan4
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View Affiliations Hide Affiliations1 Department of Surgical Oncology, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India 2 Department of Neurology, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India 3 Department of Psychiatry, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India 4 Centre for Biotechnology, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha 751030, India
- Source: Nanomaterials in Biological Milieu: Biomedical Applications and Environmental Sustainability , pp 120-142
- Publication Date: June 2025
- Language: English


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Healthcare has undergone an important change as a result of nanotechnology, which promises historically unseen possibilities for therapeutic, preventative, and diagnostic nanointerventions An overview of the therapeutic potential of nanoparticles (NPs) in healthcare is given in this abstract, with particular attention on how they may be used in targeted treatment, imaging, and drug delivery. Because of their special physicochemical characteristics, nanoparticles are a great option to get beyond conventional medication delivery restrictions. Their control over drug release kinetics is made possible by their customizable size, surface chemistry, and biocompatibility, which maximizes therapeutic efficacy and reduces adverse effects. Additionally, because NPs may cross biological barriers like the blood-brain barrier, therapeutic medicines can be delivered to certain tissues or cells with precision. By enhancing solubility, preventing drug degradation, and promoting prolonged release, these nanocarriers maximize therapeutic effects. Additionally essential to medical imaging, nanoparticles offer improved contrast for diagnostic imaging. This improves monitoring, early identification, and individualized treatment plans. Targeted therapy has also been transformed by the development of nanotherapeutics, which enable controlled release and site-specific drug delivery in diseased tissues. By using ligands or antibodies on NP surfaces, active targeting technologies allow for the selective identification and binding to certain cell receptors, which enhances medication absorption by sick cells while reducing off-target effects. Notwithstanding these encouraging developments, issues with scalability, toxicity, and biocompatibility still need to be resolved before nanotherapeutics may be widely and safely used in clinical settings. This abstract underscores the transformative potential of nanoparticles in revolutionizing healthcare, paving the way for personalized and more effective therapeutic interventions across a spectrum of diseases.
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